about
Targeting cellular metabolism to improve cancer therapeuticsRegulation of mitochondrial functions by protein phosphorylation and dephosphorylationPTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients.Panepoxydone targets NF-kB and FOXM1 to inhibit proliferation, induce apoptosis and reverse epithelial to mesenchymal transition in breast cancerHigh Bak Expression Is Associated with a Favorable Prognosis in Breast Cancer and Sensitizes Breast Cancer Cells to PaclitaxelOverexpression of ErbB2 blocks Taxol-induced apoptosis by upregulation of p21Cip1, which inhibits p34Cdc2 kinaseOmniSearch: a semantic search system based on the Ontology for MIcroRNA Target (OMIT) for microRNA-target gene interaction data.Warburg effect in chemosensitivity: targeting lactate dehydrogenase-A re-sensitizes taxol-resistant cancer cells to taxolOMIT: dynamic, semi-automated ontology development for the microRNA domainMicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression.Testing for differentially-expressed microRNAs with errors-in-variables nonparametric regression.The Warburg effect in tumor progression: mitochondrial oxidative metabolism as an anti-metastasis mechanismKnockout of BRD7 results in impaired spermatogenesis and male infertility.Emerging metabolic targets in cancer therapyOvercoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism.Inhibition of the Warburg effect with a natural compound reveals a novel measurement for determining the metastatic potential of breast cancers.Identification of candidate biomarkers for the early detection of nasopharyngeal carcinoma by quantitative proteomic analysis.LOC401317, a p53-regulated long non-coding RNA, inhibits cell proliferation and induces apoptosis in the nasopharyngeal carcinoma cell line HNE2.Knowledge acquisition, semantic text mining, and security risks in health and biomedical informatics.Glucose oxidation modulates anoikis and tumor metastasis.The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology.ErbB2-intronic microRNA-4728: a novel tumor suppressor and antagonist of oncogenic MAPK signalingMitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and MetastasisReceptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolismmiR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance.Heat shock factor 1 (HSF1) controls chemoresistance and autophagy through transcriptional regulation of autophagy-related protein 7 (ATG7)miR-141 is involved in BRD7-mediated cell proliferation and tumor formation through suppression of the PTEN/AKT pathway in nasopharyngeal carcinomaStalling the engine of resistance: targeting cancer metabolism to overcome therapeutic resistance.Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1αManganese superoxide dismutase promotes anoikis resistance and tumor metastasisMicroRNA-16 sensitizes breast cancer cells to paclitaxel through suppression of IKBKB expression.A regulatory circuit of miR-125b/miR-20b and Wnt signalling controls glioblastoma phenotypes through FZD6-modulated pathways.The development of non-coding RNA ontology.miR-125b regulates differentiation and metabolic reprogramming of T cell acute lymphoblastic leukemia by directly targeting A20.Elevated microRNA-125b levels predict a worse prognosis in HER2-positive breast cancer patientsOMIT: a domain-specific knowledge base for microRNA target prediction.BRD7 plays an anti-inflammatory role during early acute inflammation by inhibiting activation of the NF-кB signaling pathway.SON and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes.Determination of Breast Cancer Cell Migratory Ability.SPLUNC1 is associated with nasopharyngeal carcinoma prognosis and plays an important role in all-trans-retinoic acid-induced growth inhibition and differentiation in nasopharyngeal cancer cells.
P50
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P50
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onderzoeker
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հետազոտող
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Ming Tan
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Ming Tan
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Ming Tan
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Ming Tan
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Ming Tan
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Ming Tan
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P1153
P106
P1153
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P31
P496
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