about
Aprataxin, a novel protein that protects against genotoxic stressCompetitive evaluation of data mining algorithms for use in classification of leukocyte subtypes with Raman microspectroscopy.Identification of Key Proteins in Human Epithelial Cells Responding to Bystander Signals From Irradiated Trout Skin.Non-thermal atmospheric plasma induces ROS-independent cell death in U373MG glioma cells and augments the cytotoxicity of temozolomide.Vibrational spectroscopy in sensing radiobiological effects: analyses of targeted and non-targeted effects in human keratinocytes.Silver nanoparticles induce pro-inflammatory gene expression and inflammasome activation in human monocytes.[Cu(o-phthalate)(phenanthroline)] Exhibits Unique Superoxide-Mediated NCI-60 Chemotherapeutic Action through Genomic DNA Damage and Mitochondrial Dysfunction.The Antibacterial Activity of Metal Complexes Containing 1,10- phenanthroline: Potential as Alternative Therapeutics in the Era of Antibiotic Resistance.Regulating bioactivity of Cu2+ bis-1,10-phenanthroline artificial metallonucleases with sterically functionalized pendant carboxylates.Radical-induced DNA damage by cytotoxic square-planar copper(II) complexes incorporating o-phthalate and 1,10-phenanthroline or 2,2'-dipyridyl.Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and rEvaluation of the potential of Raman microspectroscopy for prediction of chemotherapeutic response to cisplatin in lung adenocarcinoma.Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial dysfunction.Apoptosis is signalled early by low doses of ionising radiation in a radiation-induced bystander effect.Targeting the folate receptor: improving efficacy in inorganic medicinal chemistry.Water-soluble and photo-stable silver(I) dicarboxylate complexes containing 1,10-phenanthroline ligands: Antimicrobial and anticancer chemotherapeutic potential, DNA interactions and antioxidant activity.Doxorubicin kinetics and effects on lung cancer cell lines using in vitro Raman micro-spectroscopy: binding signatures, drug resistance and DNA repair.Prediction of DNA damage and G2 chromosomal radio-sensitivity ex vivo in peripheral blood mononuclear cells with label-free Raman micro-spectroscopyA novel form of ataxia oculomotor apraxia characterized by oxidative stress and apoptosis resistanceIn vitro evaluation of the cytotoxicity of a folate-modified β-cyclodextrin as a new anti-cancer drug delivery systemWater-soluble bis(1,10-phenanthroline) octanedioate Cu2+ and Mn2+ complexes with unprecedented nano and picomolar in vitro cytotoxicity: promising leads for chemotherapeutic drug developmentDo Radiation-Induced Bystander Effects Correlate to the Intrinsic Radiosensitivity of Individuals and Have Clinical Significance?Bis-phenanthroline copper(ii) phthalate complexes are potent in vitro antitumour agents with ‘self-activating’ metallo-nuclease and DNA binding propertiesQuantitative reagent-free detection of fibrinogen levels in human blood plasma using Raman spectroscopyRaman Spectroscopy As A Potential Rapid Screening Tool For Venous ThromboembolismCell Death Mechanisms Associated with G2Radiosensitivity in Patients with Prostate Cancer and Benign Prostatic HyperplasiaTetrameric and polymeric silver complexes of the omeprazole scaffold; synthesis, structure, in vitro and in vivo antimicrobial activities and DNA interactionThe G2 chromosomal radiosensitivity assayDNA cleavage reactions of the dinuclear chemotherapeutic agent copper(II) bis-1,10- phenanthroline terephthalateIn-vivo evaluation of the response of Galleria mellonella larvae to novel copper(II) phenanthroline-phenazine complexesCu(ii) phenanthroline-phenazine complexes dysregulate mitochondrial function and stimulate apoptosisCopper(II) complexes of coumarin-derived Schiff base ligands: Pro- or antioxidant activity in MCF-7 cells?
P50
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Orla Howe
@ast
Orla Howe
@en
Orla Howe
@es
Orla Howe
@nl
type
label
Orla Howe
@ast
Orla Howe
@en
Orla Howe
@es
Orla Howe
@nl
prefLabel
Orla Howe
@ast
Orla Howe
@en
Orla Howe
@es
Orla Howe
@nl
P106
P1153
55932984800
P31
P496
0000-0002-5150-022X