about
Crystal structure of the β2 adrenergic receptor-Gs protein complexPositive allosteric modulation of the human metabotropic glutamate receptor 4 (hmGluR4) by SIB-1893 and MPEPThe metabotropic glutamate receptor 4 is internalized and desensitized upon protein kinase C activationCrystal structure of the µ-opioid receptor bound to a morphinan antagonistOn the mechanism of interaction of potent surmountable and insurmountable antagonists with the prostaglandin D2 receptor CRTH2Novel selective thiazoleacetic acids as CRTH2 antagonists developed from in silico derived hits. Part 2.Antagonism of the prostaglandin D2 receptor CRTH2 attenuates asthma pathology in mouse eosinophilic airway inflammation.Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators.Pharmacological characterization and modeling of the binding sites of novel 1,3-bis(pyridinylethynyl)benzenes as metabotropic glutamate receptor 5-selective negative allosteric modulators.A new metabotropic glutamate receptor agonist with in vivo anti-allodynic activity.Real-time trafficking and signaling of the glucagon-like peptide-1 receptor.mGluR5: exploration of orthosteric and allosteric ligand binding pockets and their applications to drug discovery.Structure-activity relationships for negative allosteric mGluR5 modulators.Identification of indole derivatives exclusively interfering with a G protein-independent signaling pathway of the prostaglandin D2 receptor CRTH2.A cAMP Biosensor-Based High-Throughput Screening Assay for Identification of Gs-Coupled GPCR Ligands and Phosphodiesterase Inhibitors.Novel selective orally active CRTH2 antagonists for allergic inflammation developed from in silico derived hitscAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors
P50
Q24635327-DC5FB676-C55D-47DA-88D0-7E55A60C2A71Q24672796-DF3A9615-E10E-494B-9F22-ED7CC1BDF304Q24675679-543F2776-CBB2-4EC8-AA41-DACC29D08303Q27678133-593DCA15-0B91-4F5E-BAD1-BE6C061201FEQ28292274-B2F0FF03-CD7D-48DC-BB2F-808C84362D11Q33519830-F5764C77-1071-4C0A-8BDB-4F7E876FCD62Q35663953-2E7AAE21-89DB-498C-A012-60F908692DF9Q36263703-477ED73E-2841-4842-A36E-04D756DC99E2Q39296006-5250C121-3729-4BE2-A61C-14C62127A5B6Q42967354-3D7D9928-1E96-4288-A8E8-00B50CACD6EAQ44157653-6159D002-0EFF-41AA-A727-C71B7156EA7FQ44988763-FAD80476-B2FD-495F-A294-D0902425E65DQ46201182-F4A40067-6DEB-4040-BD38-5663B3E2CA52Q46471412-D92CFD1C-25B0-43A3-A18C-EF18AEE27A1CQ53551796-9793F250-E4C4-43CD-AA30-8AD1ED80A6F6Q79416333-C20761D2-DCE5-494F-8EF6-5D02896B106CQ86041154-2C60D5C2-B952-4D0D-AD72-6B4FCC8A4426
P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Jesper M Mathiesen
@ast
Jesper M Mathiesen
@en
Jesper M Mathiesen
@es
Jesper M Mathiesen
@nl
type
label
Jesper M Mathiesen
@ast
Jesper M Mathiesen
@en
Jesper M Mathiesen
@es
Jesper M Mathiesen
@nl
prefLabel
Jesper M Mathiesen
@ast
Jesper M Mathiesen
@en
Jesper M Mathiesen
@es
Jesper M Mathiesen
@nl
P106
P1153
8714895100
P31
P496
0000-0003-4251-4416