Estimating metabolic rate for butadiene at steady state using a Bayesian physiologically-based pharmacokinetic model

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Estimating metabolic rate for butadiene at steady state using a Bayesian physiologically-based pharmacokinetic model

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im Oktober 2009 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2009

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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Estimating metabolic rate for ...... ly-based pharmacokinetic model

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P1476

Estimating metabolic rate for ...... ly-based pharmacokinetic model

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P2093

Frédéric Y. Bois

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Long Ngo

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Louise M. Ryan

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Maura Mezzetti

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Thomas J. Smith

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P2860

Human physiologic factors in respiratory uptake of 1,3-butadiene.

Association of the blood/air partition coefficient of 1,3-butadiene with blood lipids and albumin

Optimal design for a study of butadiene toxicokinetics in humans.

Species differences in the distribution of inhaled butadiene in tissues.

Gender and species differences in the metabolism of 1,3-butadiene to butadiene monoepoxide and butadiene diepoxide in rodents following low-level inhalation exposures.

Species differences in the production and clearance of 1,3-butadiene metabolites: a mechanistic model indicates predominantly physiological, not biochemical, control.

A physiological toxicokinetic model for 1,3-butadiene in rodents and man: blood concentrations of 1,3-butadiene, its metabolically formed epoxides, and of haemoglobin adducts--relevance of glutathione depletion.

Physiological Pharmacokinetic Analysis Using Population Modeling and Informative Prior Distributions

P2888

s10651-009-0124-1

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131-146

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scholarly article

P356

10.1007/S10651-009-0124-1

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P478

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2009-10-21T00:00:00Z

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