about
Allosteric regulation of catalytic activity: Escherichia coli aspartate transcarbamoylase versus yeast chorismate mutaseSexual diploids of Aspergillus nidulans do not form by random fusion of nuclei in the heterokaryonThe temporal dynamics of differential gene expression in Aspergillus fumigatus interacting with human immature dendritic cells in vitroIdentification of Aspergillus fumigatus Surface Components That Mediate Interaction of Conidia and Hyphae With Human Platelets.CRISPR-Cas9, the new kid on the block of fungal molecular biology.ImmunoPET/MR imaging allows specific detection of Aspergillus fumigatus lung infection in vivoRegulation of sulphur assimilation is essential for virulence and affects iron homeostasis of the human-pathogenic mould Aspergillus fumigatus.Pathogenic fungi regulate immunity by inducing neutrophilic myeloid-derived suppressor cells.RNAseq analysis of Aspergillus fumigatus in blood reveals a just wait and see resting stage behaviorAn eight-subunit COP9 signalosome with an intact JAMM motif is required for fungal fruit body formation.Nitrogen metabolism of Aspergillus and its role in pathogenicity.Chitin synthases with a myosin motor-like domain control the resistance of Aspergillus fumigatus to echinocandins.Exploration of Sulfur Assimilation of Aspergillus fumigatus Reveals Biosynthesis of Sulfur-Containing Amino Acids as a Virulence Determinant.Mutant characterization and in vivo conditional repression identify aromatic amino acid biosynthesis to be essential for Aspergillus fumigatus virulence.The putative alpha-1,2-mannosyltransferase AfMnt1 of the opportunistic fungal pathogen Aspergillus fumigatus is required for cell wall stability and full virulenceExogenous TNFR2 activation protects from acute GvHD via host T reg cell expansion.Phagocyte responses towards Aspergillus fumigatus.Platelets as immune cells in infectious diseases.Genetic surgery in fungi: employing site-specific recombinases for genome manipulation.How to invade a susceptible host: cellular aspects of aspergillosis.Generation of a multipathogen-specific T-cell product for adoptive immunotherapy based on activation-dependent expression of CD154.Systematic Identification of Anti-Fungal Drug Targets by a Metabolic Network ApproachThe novel Aspergillus fumigatus MAT1-2-4 mating-type gene is required for mating and cleistothecia formation.When Green and Red Mycology Meet: Impressions From an Interdisciplinary Forum on Virulence Mechanisms of Phyto- and Human-Pathogenic Fungi.Conserved regulators of mating are essential for Aspergillus fumigatus cleistothecium formationUpgrading fungal gene expression on demand: improved systems for doxycycline-dependent silencing in Aspergillus fumigatus.Human dendritic cell subsets display distinct interactions with the pathogenic mould Aspergillus fumigatus.The asexual pathogen aspergillus fumigatus expresses functional determinants of Aspergillus nidulans sexual development.Deciphering metabolic traits of the fungal pathogen Aspergillus fumigatus: redundancy vs. essentiality.Current challenges of research on filamentous fungi in relation to human welfare and a sustainable bio-economy: a white paper.Validation of a self-excising marker in the human pathogen Aspergillus fumigatus by employing the beta-rec/six site-specific recombination system.Lightning up the worm: How to probe fungal virulence in an alternative mini-host by bioluminescence.Deletion and allelic exchange of the Aspergillus fumigatus veA locus via a novel recyclable marker module.Deletion of Aspergillus nidulans aroC using a novel blaster module that combines ET cloning and marker rescue.Oligopeptide transport and regulation of extracellular proteolysis are required for growth of Aspergillus fumigatus on complex substrates but not for virulence.Tet-on, or Tet-off, that is the question: Advanced conditional gene expression in Aspergillus.VelB/VeA/LaeA complex coordinates light signal with fungal development and secondary metabolism.The Aspergillus nidulans F-box protein GrrA links SCF activity to meiosis.The COP9 signalosome is an essential regulator of development in the filamentous fungus Aspergillus nidulans.Surface display of Gaussia princeps luciferase allows sensitive fungal pathogen detection during cutaneous aspergillosis.
P50
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P50
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onderzoeker
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հետազոտող
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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Sven Krappmann
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P106
P21
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0000-0002-8299-7777
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viaf-8279398