about
Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell developmentESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoformsGata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic developmentRunx genes are direct targets of Scl/Tal1 in the yolk sac and fetal liverHematopoietic stem cells localize to the endothelial cell layer in the midgestation mouse aorta.Identification of novel regulators of hematopoietic stem cell development through refinement of stem cell localization and expression profiling.Developmental origins of hematopoietic stem cells.Genome-wide analysis of simultaneous GATA1/2, RUNX1, FLI1, and SCL binding in megakaryocytes identifies hematopoietic regulators.SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development.High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in miceGATA-2 plays two functionally distinct roles during the ontogeny of hematopoietic stem cellsDlk1 is a negative regulator of emerging hematopoietic stem and progenitor cells.Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cellsEndoglin expression in blood and endothelium is differentially regulated by modular assembly of the Ets/Gata hemangioblast codeThe placenta as a haematopoietic organ.Concise review: From greenhouse to garden: the changing soil of the hematopoietic stem cell microenvironment during development.Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development.Gfi1 expression is controlled by five distinct regulatory regions spread over 100 kilobases, with Scl/Tal1, Gata2, PU.1, Erg, Meis1, and Runx1 acting as upstream regulators in early hematopoietic cells.Embryonal subregion-derived stromal cell lines from novel temperature-sensitive SV40 T antigen transgenic mice support hematopoiesis.cis-Regulatory remodeling of the SCL locus during vertebrate evolution.JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F-positive essential thrombocythemia.Analysis of Jak2 signaling reveals resistance of mouse embryonic hematopoietic stem cells to myeloproliferative disease mutation.Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.Molecular processes involved in B cell acute lymphoblastic leukaemia.The unconventional embryo: immune-restricted potential precedes multipotentiality.Analysis of the mouse placenta as a hematopoietic stem cell niche.The murine placenta contains hematopoietic stem cells within the vascular labyrinth region.A310 helical turn is essential for the proliferation-inhibiting properties of macrophage inflammatory protein-1 alpha (CCL3)Macrophage inflammatory protein-1alpha uses a novel receptor for primitive hemopoietic cell inhibitionThe multi-faceted role of Gata3 in developmental haematopoiesisThe fetal liver lymphoid-primed multipotent progenitor provides the prerequisites for the initiation of t(4;11) MLL-AF4 infant leukemiaAn Unexpected Role for IL-3 in the Embryonic Development of Hematopoietic Stem CellsHematopoietic stem cell transplantation alters susceptibility to pulmonary hypertension in Bmpr2-deficient miceEndothelial-to-haematopoietic transition: an update on the process of making bloodThe Ly‐6A (Sca‐1) GFP Transgene is Expressed in all Adult Mouse Hematopoietic Stem CellsGata3 targets Runx1 in the embryonic haematopoietic stem cell niche
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Katrin Ottersbach
@ast
Katrin Ottersbach
@en
Katrin Ottersbach
@es
Katrin Ottersbach
@nl
type
label
Katrin Ottersbach
@ast
Katrin Ottersbach
@en
Katrin Ottersbach
@es
Katrin Ottersbach
@nl
prefLabel
Katrin Ottersbach
@ast
Katrin Ottersbach
@en
Katrin Ottersbach
@es
Katrin Ottersbach
@nl
P108
P106
P1153
6603342524
P31
P496
0000-0002-6880-4895