Peroxisomal MAVS activates IRF1-mediated IFN-λ production - Wikidata - awgldk - TriplyDB

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

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Interferon induction by RNA viruses and antagonism by viral pathogens Zinc is a potent and specific inhibitor of IFN-λ3 signalling.Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans.Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus.Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses Spontaneous activation of a MAVS-dependent antiviral signaling pathway determines high basal interferon-β expression in cardiac myocytes.Epigenetic silencing of IRF1 dysregulates type III interferon responses to respiratory virus infection in epithelial to mesenchymal transition.Molecular cloning and functional characterization of feline MAVS.Infection Elicited Autoimmunity and Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: An Explanatory Model.Peroxisomes support human herpesvirus 8 latency by stabilizing the viral oncogenic protein vFLIP via the MAVS-TRAF complex.

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Peroxisomal MAVS activates IRF1-mediated IFN-λ production

http://www.wikidata.org/entity/Q57236572

description

article

@en

im Juli 2014 veröffentlichter wissenschaftlicher Artikel

@de

wetenschappelijk artikel

@nl

наукова стаття, опублікована в липні 2014

@uk

name

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

@en

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

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type

label

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

@en

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

@nl

prefLabel

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

@en

Peroxisomal MAVS activates IRF1-mediated IFN-λ production

@nl

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Nature Immunology

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Peroxisomal MAVS activates IRF1-mediated IFN-λ production

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Michael D Robek

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Peroxisomes are signaling platforms for antiviral innate immunity

Interferon-inducible cholesterol-25-hydroxylase broadly inhibits viral entry by production of 25-hydroxycholesterol

IFN-lambda (IFN-lambda) is expressed in a tissue-dependent fashion and primarily acts on epithelial cells in vivo.

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

HCV infection induces a unique hepatic innate immune response associated with robust production of type III interferons

Cell intrinsic immunity spreads to bystander cells via the intercellular transfer of cGAMP.

Prion-like polymerization underlies signal transduction in antiviral immune defense and inflammasome activation.

Hepatitis C virus pathogen associated molecular pattern (PAMP) triggers production of lambda-interferons by human plasmacytoid dendritic cells

Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus.

Hepatitis C virus induces interferon-λ and interferon-stimulated genes in primary liver cultures.

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700-701

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scholarly article

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10.1038/NI.2924

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8

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15

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2014-07-21T00:00:00Z

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25045870

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