Systemic Deficiency of the MAP Kinase–Activated Protein Kinase 2 Reduces Atherosclerosis in Hypercholesterolemic Mice
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Distinct roles of MK2 and MK5 in cAMP/PKA- and stress/p38MAPK-induced heat shock protein 27 phosphorylationMAPKAP kinase MK2 maintains self-renewal capacity of haematopoietic stem cellsMAP-Kinase Activated Protein Kinase 2 Links Endothelial Activation and Monocyte/macrophage Recruitment in ArteriogenesisRole of suppressor of cytokine signaling-1 in murine atherosclerosisComplex regulation and function of the inflammatory smooth muscle cell phenotype in atherosclerosisEndothelial and macrophage-specific deficiency of P38α MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice.Design of a bioactive cell-penetrating peptide: when a transduction domain does more than transduceDifferential impact of familial hypercholesterolemia and combined hyperlipidemia on vascular wall and network remodeling in mice.Mitogen-activated protein kinase-activated protein kinase 2 deficiency reduces insulin sensitivity in high-fat diet-fed mice.Common therapeutic targets in cardiometabolic diseaseActivation of calcium/calmodulin-dependent protein kinase II in obesity mediates suppression of hepatic insulin signaling.Peptide inhibitors of MK2 show promise for inhibition of abdominal adhesionsMitogen-activated protein kinase signalling and ERK1/2 bistability in asthma.MAPK usage in periodontal disease progression.Genetic basis of atherosclerosis: insights from mice and humansTreatment of Obese Insulin-Resistant Mice With an Allosteric MAPKAPK2/3 Inhibitor Lowers Blood Glucose and Improves Insulin SensitivityReactive Oxygen Species, SUMOylation, and Endothelial InflammationPivotal Role of Mitogen-Activated Protein Kinase-Activated Protein Kinase 2 in Inflammatory Pulmonary Diseases.MK2 inhibitor reduces alkali burn-induced inflammation in rat cornea.Macrophage deficiency of p38alpha MAPK promotes apoptosis and plaque necrosis in advanced atherosclerotic lesions in miceNormal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice.Low-molecular-weight MK2 inhibitors: a tough nut to crack!Molecular biology of atherosclerosis.Roles of p38α mitogen-activated protein kinase in mouse models of inflammatory diseases and cancer.Inflammatory processes in cardiovascular disease: a route to targeted therapies.Flow signaling and atherosclerosis.TGF-β inhibits the uptake of modified low density lipoprotein by human macrophages through a Smad-dependent pathway: a dominant role for Smad-2.The Role of Mitogen-Activated Protein Kinase-Activated Protein Kinases (MAPKAPKs) in Inflammation.Hypoxia and kinase activity regulate lung epithelial cell glutathione.Collagen-binding nanoparticles for extracellular anti-inflammatory peptide delivery decrease platelet activation, promote endothelial migration, and suppress inflammation.
P2860
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P2860
Systemic Deficiency of the MAP Kinase–Activated Protein Kinase 2 Reduces Atherosclerosis in Hypercholesterolemic Mice
description
im November 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2007
@uk
name
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@en
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@nl
type
label
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@en
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@nl
prefLabel
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@en
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@nl
P2093
P1433
P1476
Systemic Deficiency of the MAP ...... s in Hypercholesterolemic Mice
@en
P2093
Bernhard Schieffer
Helmut Drexler
Kumaravelu Jagavelu
Udo Bavendiek
Uwe J.F. Tietge
P304
P356
10.1161/CIRCRESAHA.107.156075
P577
2007-11-26T00:00:00Z