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Visualizing the Translocation and Localization of Bacterial Type III Effector Proteins by Using a Genetically Encoded Reporter System.Microsporidia: Why Make Nucleotides if You Can Steal Them?The enteropathogenic E. coli effector EspF targets and disrupts the nucleolus by a process regulated by mitochondrial dysfunctionThe enteropathogenic E. coli (EPEC) Tir effector inhibits NF-κB activity by targeting TNFα receptor-associated factorsThe bacterial cytoskeleton modulates motility, type 3 secretion, and colonization in SalmonellaPotent diarrheagenic mechanism mediated by the cooperative action of three enteropathogenic Escherichia coli-injected effector proteins.Insights into the pathogenesis of enteropathogenic E. coli using an improved intestinal enterocyte modelThe effector repertoire of enteropathogenic E. coli: ganging up on the host cellEPEC's weapons of mass subversion.The EspF effector, a bacterial pathogen's Swiss army knifeFunctional domains and motifs of bacterial type III effector proteins and their roles in infection.Transport proteins of parasitic protists and their role in nutrient salvage.Cell-surface nucleolin is sequestered into EPEC microcolonies and may play a role during infection.Cultured enterocytes internalise bacteria across their basolateral surface for, pathogen-inhibitable, trafficking to the apical compartment.Eicosanoid involvement in the regulation of behavioral fever in the desert locust, Schistocerca gregaria.Do Caco-2 subclones provide more appropriate in vitro models for understanding how human enteric pathogens cause disease?The enteropathogenic Escherichia coli EspF effector molecule inhibits PI-3 kinase-mediated uptake independently of mitochondrial targeting.Evolutionary conservation and in vitro reconstitution of microsporidian iron-sulfur cluster biosynthesis.Plasma membrane-located purine nucleotide transport proteins are key components for host exploitation by microsporidian intracellular parasites.Complete genome sequence and comparative genome analysis of enteropathogenic Escherichia coli O127:H6 strain E2348/69.A bacterial encoded protein induces extreme multinucleation and cell-cell internalization in intestinal cells.The bacterial effectors EspG and EspG2 induce a destructive calpain activity that is kept in check by the co-delivered Tir effector.Hyperphagocytic haemocytes in Manduca sexta.Microbial infection causes the appearance of hemocytes with extreme spreading ability in monolayers of the tobacco hornworm Manduca sexta.Modulation by eicosanoid biosynthesis inhibitors of immune responses by the insect Manduca sexta to the pathogenic fungus Metarhizium anisopliae.Bacterial infection of a model insect: Photorhabdus luminescens and Manduca sexta.Intestinal barrier dysfunction by enteropathogenic Escherichia coli is mediated by two effector molecules and a bacterial surface protein.Cell of the month: An insect blood cell engulfing bacteria.Enteropathogenic Escherichia coli (EPEC) effector-mediated suppression of antimicrobial nitric oxide production in a small intestinal epithelial model system.Transporter gene acquisition and innovation in the evolution of Microsporidia intracellular parasites.Regulation of phagosome functions by post-translational modifications: a new paradigm
P50
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P50
description
onderzoeker
@nl
researcher ORCID: 0000-0002-2822-4677
@en
name
Paul Dean
@ast
Paul Dean
@en
Paul Dean
@es
Paul Dean
@nl
باول دين
@ar
type
label
Paul Dean
@ast
Paul Dean
@en
Paul Dean
@es
Paul Dean
@nl
باول دين
@ar
prefLabel
Paul Dean
@ast
Paul Dean
@en
Paul Dean
@es
Paul Dean
@nl
باول دين
@ar
P106
P21
P31
P496
0000-0002-2822-4677