Direct and GTP-dependent Interaction of ADP-ribosylation Factor 1 with Clathrin Adaptor Protein AP-1 on Immature Secretory Granules
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Islet cell autoantigen of 69 kDa is an arfaptin-related protein associated with the Golgi complex of insulinoma INS-1 cellsA large-scale conformational change couples membrane recruitment to cargo binding in the AP2 clathrin adaptor complexPACS-1 binding to adaptors is required for acidic cluster motif-mediated protein traffic.Functional and physical interactions of the adaptor protein complex AP-4 with ADP-ribosylation factors (ARFs).AP-1 recruitment to VAMP4 is modulated by phosphorylation-dependent binding of PACS-1Structures and mechanisms of vesicle coat components and multisubunit tethering complexesLaa1p, a conserved AP-1 accessory protein important for AP-1 localization in yeast.Non-stoichiometric relationship between clathrin heavy and light chains revealed by quantitative comparative proteomics of clathrin-coated vesicles from brain and liverSynaptotagmin IV is necessary for the maturation of secretory granules in PC12 cellsGGAs: roles of the different domains and comparison with AP-1 and clathrinThe Arf family G protein Arl1 is required for secretory granule biogenesis in Drosophila.ARF1.GTP, tyrosine-based signals, and phosphatidylinositol 4,5-bisphosphate constitute a minimal machinery to recruit the AP-1 clathrin adaptor to membranes.Trans-Golgi network sorting.Vesicular protein transport.AP-1 membrane-cytoplasm recycling regulated by mu1A-adaptin.Coatomer and dimeric ADP ribosylation factor 1 promote distinct steps in membrane scissionADP ribosylation factor 1 activity is required to recruit AP-1 to the major histocompatibility complex class I (MHC-I) cytoplasmic tail and disrupt MHC-I trafficking in HIV-1-infected primary T cells.Binding of cargo sorting signals to AP-1 enhances its association with ADP ribosylation factor 1-GTP.Discovery and progress in our understanding of the regulated secretory pathway in neuroendocrine cells.Homotypic fusion of immature secretory granules during maturation requires syntaxin 6Role of adaptor proteins in secretory granule biogenesis and maturationNegative effects of desiccation on the protein sorting and post-translational modification.Modulation of dendritic spine development and plasticity by BDNF and vesicular trafficking: fundamental roles in neurodevelopmental disorders associated with mental retardation and autismRedundant roles of BIG2 and BIG1, guanine-nucleotide exchange factors for ADP-ribosylation factors in membrane traffic between the trans-Golgi network and endosomesSyntaxin 6 regulates Glut4 trafficking in 3T3-L1 adipocytes.GGA function is required for maturation of neuroendocrine secretory granules.Regulation and recruitment of phosphatidylinositol 4-kinase on immature secretory granules is independent of ADP-ribosylation factor 1.Toxoplasma gondii ADP-ribosylation factor 1 mediates enhanced release of constitutively secreted dense granule proteins.Trafficking of yellow-fluorescent-protein-tagged mu1 subunit of clathrin adaptor AP-1 complex in living cells.The structure of RalF, an ADP-ribosylation factor guanine nucleotide exchange factor from Legionella pneumophila, reveals the presence of a cap over the active site.A conformational change in the alpha-subunit of coatomer induced by ligand binding to gamma-COP revealed by single-pair FRET.Scission of COPI and COPII vesicles is independent of GTP hydrolysis.
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P2860
Direct and GTP-dependent Interaction of ADP-ribosylation Factor 1 with Clathrin Adaptor Protein AP-1 on Immature Secretory Granules
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Juli 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в травні 2000
@uk
name
Direct and GTP-dependent Inter ...... on Immature Secretory Granules
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Direct and GTP-dependent Inter ...... on Immature Secretory Granules
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type
label
Direct and GTP-dependent Inter ...... on Immature Secretory Granules
@en
Direct and GTP-dependent Inter ...... on Immature Secretory Granules
@nl
prefLabel
Direct and GTP-dependent Inter ...... on Immature Secretory Granules
@en
Direct and GTP-dependent Inter ...... on Immature Secretory Granules
@nl
P2860
P356
P1476
Direct and GTP-dependent inter ...... on immature secretory granules
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P2093
P2860
P304
21862-21869
P356
10.1074/JBC.M908875199
P407
P50
P577
2000-07-01T00:00:00Z