High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
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Regulation generation: the suppressive functions of human regulatory T cellsHomeostasis and function of regulatory T cells (Tregs) in vivo: lessons from TCR-transgenic TregsTrauma equals danger--damage control by the immune systemOral tolerance to food proteinαβ T cell receptors as predictors of health and diseaseMHC-derived allopeptide activates TCR-biased CD8+ Tregs and suppresses organ rejection.Trafficking of regulatory T cells in the intestinal immune system.Full activation of CD4+ T cells early during sepsis requires specific antigen.High-throughput sequencing of islet-infiltrating memory CD4+ T cells reveals a similar pattern of TCR Vβ usage in prediabetic and diabetic NOD miceRequirement of full TCR repertoire for regulatory T cells to maintain intestinal homeostasisEnhanced renewal of regulatory T cells in relation to CD4(+) conventional T lymphocytes in the peripheral compartment.Cutting edge: IL-2 signals determine the degree of TCR signaling necessary to support regulatory T cell proliferation in vivoCD4+VEGFR1(HIGH) T cell as a novel Treg subset regulates inflammatory bowel disease in lymphopenic miceContext and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditionsDynamic changes of circulating T-helper cell subsets following severe thoracic trauma.IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapyGeneration and function of induced regulatory T cells.T cell populations in the pancreatic lymph node naturally and consistently expand and contract in NOD mice as disease progresses.IMGT/HighV QUEST paradigm for T cell receptor IMGT clonotype diversity and next generation repertoire immunoprofiling.The past, present, and future of immune repertoire biology - the rise of next-generation repertoire analysis.Chronic follicular bronchiolitis requires antigen-specific regulatory T cell control to prevent fatal disease progression.Distribution and clonality of the vα and vβ T-cell receptor repertoire of regulatory T cells in leukemia patients with and without graft versus host disease.TCR diversity and Treg cells, sometimes more is more.Modeling the T cell immune response: a fascinating challenge.Intestinal mucosal tolerance and impact of gut microbiota to mucosal toleranceDynamics of Individual T Cell Repertoires: From Cord Blood to Centenarians.How antigen specificity directs regulatory T-cell function: self, foreign and engineered specificity.The Lower Limit of Regulatory CD4+ Foxp3+ TCRβ Repertoire Diversity Required To Control Autoimmunity.Deep sequencing of the TCR-β repertoire of human forkhead box protein 3 (FoxP3)+ and FoxP3- T cells suggests that they are completely distinct and non-overlapping.Foxp3(+) T cells expressing RORγt represent a stable regulatory T-cell effector lineage with enhanced suppressive capacity during intestinal inflammation.Site-specific accumulation of recently activated CD4+ Foxp3+ regulatory T cells following adoptive transfer.TCR sequences and tissue distribution discriminate the subsets of naïve and activated/memory Treg cells in mice.The bone marrow of myeloma patients is steadily inhabited by a normal-sized pool of functional regulatory T cells irrespectiveof the disease status.Resident CD4+ T cells accumulate in lymphoid organs after prolonged antigen exposure.On the road to tolerance--generation and migration of gut regulatory T cells.Patients with CD3G mutations reveal a role for human CD3γ in Treg diversity and suppressive function.Induced and thymus-derived Foxp3⁺ regulatory T cells share a common niche.Immune Regulation in Hematopoietic Cell Transplantation
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P2860
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
description
im Oktober 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 18 October 2011
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 2011
@uk
name
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@en
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@nl
type
label
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@en
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@nl
prefLabel
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@en
High TCR diversity ensures optimal function andhomeostasis of Foxp3+regulatory Tcells
@nl
P2093
P2860
P50
P356
P1476
High TCR diversity ensures optimal function and homeostasis of Foxp3+ regulatory T cells
@en
P2093
André Bleich
Benjamin Wahl
Chun-Wei Lee
Cornelia Lindner
Günter J Hämmerling
Jan D Haas
Janine Suffner
Lisa Föhse
Stella Lamprecht
Susanne Schmitz
P2860
P304
P356
10.1002/EJI.201141986
P407
P577
2011-10-18T00:00:00Z