Copper Catalyzed Assembly ofN-Aryloxazolidinones: Synthesis of Linezolid, Tedizolid, and Rivaroxaban

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Copper Catalyzed Assembly ofN-Aryloxazolidinones: Synthesis of Linezolid, Tedizolid, and Rivaroxaban

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im Februar 2016 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в лютому 2016

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Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

@en

Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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P1476

Copper Catalyzed Assembly ofN- ...... id, Tedizolid, and Rivaroxaban

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P2093

Christopher G. Frost

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Jamie A. Leitch

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William Mahy

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P2860

Design at the atomic level: design of biaryloxazolidinones as potent orally active antibiotics

Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor

Oxazolidinone structure-activity relationships leading to linezolid.

Synthesis and antibacterial activity of U-100592 and U-100766, two oxazolidinone antibacterial agents for the potential treatment of multidrug-resistant gram-positive bacterial infections.

CuBr/rac-BINOL-catalyzed N-arylations of aliphatic amines at room temperature.

An efficient process for pd-catalyzed C-N cross-coupling reactions of aryl iodides: insight into controlling factors.

The discovery and development of rivaroxaban, an oral, direct factor Xa inhibitor.

Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations.

Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-Fluoro-4- (1-oxotetrahydrothiopyran-4-yl)phenyl]-2- oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound.

A new copper acetate-bis(oxazoline)-catalyzed, enantioselective Henry reaction.

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1305-1313

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P31

scholarly article

P356

10.1002/EJOC.201600033

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P433

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P478

2016

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2016-02-09T00:00:00Z

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