about
Ca2+ permeability of nicotinic acetylcholine receptors from rat dorsal root ganglion neuronesEnhancement of GABA(A)-current run-down in the hippocampus occurs at the first spontaneous seizure in a model of temporal lobe epilepsy.LAV-BPIFB4 isoform modulates eNOS signalling through Ca2+/PKC-alpha-dependent mechanismGenetic Analysis Reveals a Longevity-Associated Protein Modulating Endothelial Function and Angiogenesis.Design, synthesis, and pharmacological characterization of novel spirocyclic quinuclidinyl-Δ2-isoxazoline derivatives as potent and selective agonists of α7 nicotinic acetylcholine receptors.Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype.Crucial role of nicotinic α5 subunit variants for Ca2+ fluxes in ventral midbrain neuronsCC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation.Adenosine receptor antagonists alter the stability of human epileptic GABAA receptors.Chemistry and Pharmacology of a Series of Unichiral Analogues of 2-(2-Pyrrolidinyl)-1,4-benzodioxane, Prolinol Phenyl Ether, and Prolinol 3-Pyridyl Ether Designed as α4β2-Nicotinic Acetylcholine Receptor Agonists.FTY720 (fingolimod) is a neuroprotective and disease-modifying agent in cellular and mouse models of Huntington disease.Activation of the nicotinic acetylcholine receptor mobilizes calcium from caffeine-insensitive stores in C2C12 mouse myotubes.New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors.Modulation of the Ca(2+) permeability of human endplate acetylcholine receptor-channel.Rare missense variants of neuronal nicotinic acetylcholine receptor altering receptor function are associated with sporadic amyotrophic lateral sclerosis.Cysteine residues are critical for chemokine receptor CXCR2 functional properties.Comparison of glycine and GABA actions on the zebrafish homomeric glycine receptor.Cholinergic stimulation of human microcytoma cell line H69.Identification of a determinant of acetylcholine receptor gating kinetics in the extracellular portion of the gamma subunit.The Distribution of Charged Amino Acid Residues and the Ca2+ Permeability of Nicotinic Acetylcholine Receptors: A Predictive Model.Nicotinic cholinergic stimulation promotes survival and reduces motility of cultured rat cerebellar granule cells.Homeostatic control of synaptic activity by endogenous adenosine is mediated by adenosine kinase.About a new method to measure fractional Ca2+ currents through ligand-gated ion channels.Mechanism of verapamil action on wild-type and slow-channel mutant human muscle acetylcholine receptor.Fluoxetine prevents acetylcholine-induced excitotoxicity blocking human endplate acetylcholine receptor.Serotonin antagonizes the human neuronal alpha7 nicotinic acetylcholine receptor and becomes an agonist after L248T alpha7 mutation.Chemokine receptor CXCR2 regulates the functional properties of AMPA-type glutamate receptor GluR1 in HEK cells.Investigating the hydrogen-bond acceptor site of the nicotinic pharmacophore model: a computational and experimental study using epibatidine-related molecular probes.Electrophysiological properties of mouse bone marrow c-kit+ cells co-cultured onto neonatal cardiac myocytes.Loss of constitutive functional γ-aminobutyric acid type A-B receptor crosstalk in layer 5 pyramidal neurons of human epileptic temporal cortex.Functional properties of neurons derived from fetal mouse neurospheres are compatible with those of neuronal precursors in vivo.Expression of the K+/Cl- cotransporter, KCC2, in cerebellar Purkinje cells is regulated by group-I metabotropic glutamate receptors.Fractalkine/CX3CL1 modulates GABAA currents in human temporal lobe epilepsy.Functional properties of cells obtained from human cord blood CD34+ stem cells and mouse cardiac myocytes in coculture.From pyrrolidinyl-benzodioxane to pyrrolidinyl-pyridodioxanes, or from unselective antagonism to selective partial agonism at α4β2 nicotinic acetylcholine receptor.Bifunctional compounds targeting both D2 and non-α7 nACh receptors: design, synthesis and pharmacological characterization.Functional properties of neuronal nicotinic acetylcholine receptor channels expressed in transfected human cells.PI3Kγ inhibition reduces blood pressure by a vasorelaxant Akt/L-type calcium channel mechanismAcute and chronic effects of hypercalcaemia on cortical excitability as studied by 5 Hz repetitive transcranial magnetic stimulationCyclin D1 degradation enhances endothelial cell survival upon oxidative stress
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P50
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researcher
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wetenschapper
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հետազոտող
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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type
label
Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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Sergio Fucile
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P1153
6603852482
P21
P31
P496
0000-0003-0698-1148