Rho and Rho-kinase Mediate Thrombin-induced Phosphatidylinositol 4-Phosphate 5-Kinase Trafficking in Platelets
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Selective ROCK2 inhibition in focal cerebral ischemiaROCKs as immunomodulators of strokeRegulation of platelet plug formation by phosphoinositide metabolismArf6 plays an early role in platelet activation by collagen and convulxinRole of phosphatidylinositol-4-phosphate 5' kinase (ppk-1) in ovulation of Caenorhabditis elegans.Loss of PIP5KIgamma, unlike other PIP5KI isoforms, impairs the integrity of the membrane cytoskeleton in murine megakaryocytes.Phosphatidylinositol 4,5-bisphosphate directs spermatid cell polarity and exocyst localization in Drosophila.CCK activates RhoA and Rac1 differentially through Galpha13 and Galphaq in mouse pancreatic acini.Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2.Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNSRho-kinase inhibition improves ischemic perfusion deficit in hyperlipidemic mice.Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord.Attenuated platelet aggregation in patients with septic shock is independent from the activity state of myosin light chain phosphorylation or a reduction in Rho kinase-dependent inhibition of myosin light chain phosphatase.Regulation of the epithelial Na+ channel (ENaC) by phosphatidylinositides.Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation."Actin"g on GLUT4: membrane & cytoskeletal components of insulin action.Phospholipase D signaling: orchestration by PIP2 and small GTPases.Loss of PIP5KIbeta demonstrates that PIP5KI isoform-specific PIP2 synthesis is required for IP3 formation.Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.Ion channel regulation by Ras, Rho, and Rab small GTPases.Increased leukocyte ROCK activity in patients after acute ischemic stroke.Essential and unique roles of PIP5K-gamma and -alpha in Fcgamma receptor-mediated phagocytosis.Phospholipase D in platelets and other cells.Leucine-rich repeat-containing G-protein coupled receptor 5/GPR49 activates G12/13-Rho GTPase pathwayA Ca(2+)-dependent signalling circuit regulates influenza A virus internalization and infection.Phosphatidylinositol 5-kinase stimulates apical biosynthetic delivery via an Arp2/3-dependent mechanism.Anoctamin 6 Contributes to Cl- Secretion in Accessory Cholera Enterotoxin (Ace)-stimulated Diarrhea: AN ESSENTIAL ROLE FOR PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE (PIP2) SIGNALING IN CHOLERA.Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates.Arabidopsis phosphatidylinositol phosphate kinase 1 binds F-actin and recruits phosphatidylinositol 4-kinase beta1 to the actin cytoskeleton.Antagonistic regulation of neurite morphology through Gq/G11 and G12/G13.Phosphatidylinositol transfer protein-α in platelets is inconsequential for thrombosis yet is utilized for tumor metastasis.Phosphatidylinositol 4-Phosphate 5-Kinase β Controls Recruitment of Lipid Rafts into the Immunological Synapse.Rapid translocation and insertion of the epithelial Na+ channel in response to RhoA signaling.Hypertonic stress increases phosphatidylinositol 4,5-bisphosphate levels by activating PIP5KIbeta.
P2860
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P2860
Rho and Rho-kinase Mediate Thrombin-induced Phosphatidylinositol 4-Phosphate 5-Kinase Trafficking in Platelets
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 2004
@uk
name
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@en
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@nl
type
label
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@en
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@nl
prefLabel
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@en
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@nl
P2093
P356
P1476
Rho and Rho-kinase Mediate Thr ...... inase Trafficking in Platelets
@en
P2093
C. L. Carpenter
C. S. Abrams
S.-A. Yang
P304
42331-42336
P356
10.1074/JBC.M404335200
P407
P577
2004-07-23T00:00:00Z