about
The genetics of dilated cardiomyopathy: a prioritized candidate gene study of LMNA, TNNT2, TCAP, and PLNAPOE p.Leu167del mutation in familial hypercholesterolemia.Carboxyl-terminal disulfide bond of acid sphingomyelinase is critical for its secretion and enzymatic function.Exome sequencing in suspected monogenic dyslipidemias.Sphingomyelin phosphodiesterase-1 (SMPD1) coding variants do not contribute to low levels of high-density lipoprotein cholesterol.Analysis of lipid transfer activity between model nascent HDL particles and plasma lipoproteins: implications for current concepts of nascent HDL maturation and genesis.Genetic variation at the proprotein convertase subtilisin/kexin type 5 gene modulates high-density lipoprotein cholesterol levelsFine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjectsThe WWOX gene modulates high-density lipoprotein and lipid metabolism.Exome sequencing identifies 2 rare variants for low high-density lipoprotein cholesterol in an extended familyEffect of ABCA1 mutations on risk for myocardial infarction.Genetics of cholesterol efflux.Canadian Cardiovascular Society position statement on familial hypercholesterolemia.The HDL proteome in acute coronary syndromes shifts to an inflammatory profile.Membrane microdomains modulate oligomeric ABCA1 function: impact on apoAI-mediated lipid removal and phosphatidylcholine biosynthesisDeterminants of HDL particle size in patients with the null (P207L) or defective (D9N) mutation in the lipoprotein lipase gene: the Québec LipD Study.Characterization of LDL particle size among carriers of a defective or a null mutation in the lipoprotein lipase gene: the Québec LIPD Study.Characterization of a novel mutation causing hepatic lipase deficiency among French Canadians.Increased production of VLDL apoB-100 in subjects with familial hypercholesterolemia carrying the same null LDL receptor gene mutation.Evidence that hepatic lipase deficiency in humans is not associated with proatherogenic changes in HDL composition and metabolism.Identification of a novel human cellular HDL biosynthesis defect.Lipoprotein-associated phospholipase A(2) (Lp-PLA(2)) in acute coronary syndrome: relationship with low-density lipoprotein cholesterol.Comparison of treatment of severe high-density lipoprotein cholesterol deficiency in men with daily atorvastatin (20 mg) versus fenofibrate (200 mg) versus extended-release niacin (2 g).Quantitative analysis of ABCA1-dependent compartmentalization and trafficking of apolipoprotein A-I: implications for determining cellular kinetics of nascent high density lipoprotein biogenesis.Effects of fenofibrate on apolipoprotein kinetics in patients with coexisting dysbetalipoproteinemia and heterozygous familial hypercholesterolemia.Functional mutations of the ABCA1 gene in subjects of French-Canadian descent with HDL deficiency.Desmocollin 1 is abundantly expressed in atherosclerosis and impairs high-density lipoprotein biogenesis.Imputation of Baseline LDL Cholesterol Concentration in Patients with Familial Hypercholesterolemia on Statins or Ezetimibe.Aortic Calcification Progression in Heterozygote Familial Hypercholesterolemia.Cholesterol trapping in Niemann-Pick disease type B fibroblasts can be relieved by expressing the phosphotyrosine binding domain of GULP.High-density lipoprotein mediated cellular cholesterol efflux in acute coronary syndromes.The Essential Role of Primary Caregiver in Early Detection of Familial Hypercholesterolemia and Cardiovascular Prevention.Familial hypercholesterolemia in Canada: Initial results from the FH Canada national registryDiabetes is associated with an increased risk of cardiovascular disease in patients with familial hypercholesterolemiaIdentification of an ABCA1-dependent phospholipid-rich plasma membrane apolipoprotein A-I binding site for nascent HDL formation: implications for current models of HDL biogenesisSimplified Canadian Definition for Familial HypercholesterolemiaDisorders of high‐density lipoprotein biogenesisSevere xanthomatosis in heterozygous familial hypercholesterolemia
P50
Q28298550-65B22F68-186B-4ACF-A7AB-A746E5D7A2B3Q30355909-D89876FF-FDD9-4D46-96D1-3F29EBC77857Q30366243-9AA80299-7DEC-401A-BA58-C7A03EB39686Q30405700-816CAA4C-E3AD-4EB4-A76F-21AD562513C1Q33310999-A3D456C1-851B-4089-AE7F-DAE4185D11D6Q33741256-D10D4873-E78D-49D9-B095-95323F47438AQ33983247-4B044042-522D-4DAA-9DA8-2DE6017E1A8CQ35008788-45C539FD-9907-4B96-8C17-D0ED1B2A345BQ35042693-268B02E9-82BD-4059-8016-FFC6402480AFQ36448832-B996451A-C3D2-4D8C-9A0A-1579DCEE0057Q37244752-84214E07-FEA0-4469-8186-09102141B08DQ38005009-14175069-0E14-4C72-8DA3-D7FC7FAD249CQ38275368-B524AD5F-97DA-439A-881D-7729FC6B91C6Q38501154-8703A7D4-BCBA-41EC-91D6-C902BEE4E65DQ38745788-830F67B2-BCF1-418A-806A-7E2F7504399BQ43984099-C1989BD1-061C-4791-9CBB-12C7F30E96AFQ44063980-A5D2F604-9511-45E9-B983-154E14C8AFBDQ44460221-FB27E7CC-2306-42FA-8A39-230D7C53744FQ44766930-3EA9B42D-3991-4734-A571-3726CFDE0C22Q44919539-0A3874DE-E6EE-45E9-95FF-DF5085A2E9BBQ45954288-971CD0BE-F77A-4656-95E8-7D9DD281B65EQ46068271-E60C2FC0-0CB3-4560-B147-09F78F001688Q46257212-69311BA5-0665-467A-A978-66AEB538CE68Q46792613-281E2DEE-2166-4DDA-9541-293095A2B499Q46842192-6D03A713-2824-4B2E-BF9A-0C6F918FECD9Q46847097-F3826AFC-7F3F-4342-97A4-C4695FF177C6Q47437965-8092B2FE-25EF-45DD-AAE3-7B45F041D4E0Q47646573-80F63251-0311-4BB1-B5F7-20C152BC5966Q47780451-2E32DDD7-0EAD-42D0-B843-E1E4BFAF906FQ51754642-6F734F43-A5C5-4080-B0BF-C88F6946695EQ53083727-1FD3FBEB-6759-45D1-AFD1-953CE5013C84Q53697065-6F0F3FEA-1AD9-4146-A9DC-263B32B32617Q57052320-64b2f2af-442c-1a2a-0f2c-41fbeee65fd3Q57172854-d6e60bc8-4999-22bc-c872-b6b3693fd8c0Q57375127-6F7EFE29-1E31-41DC-9033-CBAE8DFAEB42Q57420987-9DFC8526-0B57-4D1C-BE2F-35D9F32BDC41Q58147536-28F07BA8-833A-4B57-87AE-D6201E3761E1Q64045410-E010F180-C4C5-42D3-BD8D-C561762492BC
P50
description
Canadees onderzoekster
@nl
kanadische Diätassistentin und Biochemikerin
@de
researcher ORCID ID = 0000-0002-9491-8028
@en
name
Isabelle Ruel
@ast
Isabelle Ruel
@ca
Isabelle Ruel
@en
Isabelle Ruel
@es
Isabelle Ruel
@fr
Isabelle Ruel
@ga
Isabelle Ruel
@nl
Isabelle Ruel
@sl
Isabelle Ruel
@sq
type
label
Isabelle Ruel
@ast
Isabelle Ruel
@ca
Isabelle Ruel
@en
Isabelle Ruel
@es
Isabelle Ruel
@fr
Isabelle Ruel
@ga
Isabelle Ruel
@nl
Isabelle Ruel
@sl
Isabelle Ruel
@sq
altLabel
Isabelle L Ruel
@en
Isabelle L Ruel
@fr
Isabelle L. Ruel
@en
Isabelle L. Ruel
@fr
prefLabel
Isabelle Ruel
@ast
Isabelle Ruel
@ca
Isabelle Ruel
@en
Isabelle Ruel
@es
Isabelle Ruel
@fr
Isabelle Ruel
@ga
Isabelle Ruel
@nl
Isabelle Ruel
@sl
Isabelle Ruel
@sq
P2038
Isabelle_Ruel
P21
P27
P31
P4012
P496
0000-0002-9491-8028
P6634
isabelle-ruel-98b36724