about
Consensus report on the future of animal-free systemic toxicity testingSupporting read-across using biological dataBiological and medical applications of a brain-on-a-chipA LUHMES 3D dopaminergic neuronal model for neurotoxicity testing allowing long-term exposure and cellular resilience analysis.Alzheimer disease research in the 21st century: past and current failures, new perspectives and funding prioritiesGenomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox.An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods.A human brain microphysiological system derived from induced pluripotent stem cells to study neurological diseases and toxicity.Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity.Good Cell Culture Practice for stem cells and stem-cell-derived models.Specific effect of 5-fluorouracil on alpha-fetoprotein gene expression during the in vitro mouse embryonic stem cell differentiation.Expression of Neuropathy Target Esterase in mouse embryonic stem cells during differentiation.An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE).Toward Good Read-Across Practice (GRAP) guidanceQuality assurance of metabolomics.21st Century Cell Culture for 21st Century Toxicology.Organophosphorus pesticide chlorpyrifos and its metabolites alter the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells in a comparable way to other model neurodevelopmental toxicants.Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2).Explosive Blast Loading on Human 3D Aggregate Minibrains.Brain-on-a-chip model enables analysis of human neuronal differentiation and chemotaxis.Rotenone exerts developmental neurotoxicity in a human brain spheroid model.Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation.Good cell culture practices &in vitro toxicology.Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheresA Human iPSC-derived 3D platform using primary brain cancer cells to study drug development and personalized medicineSuitability of 3D human brain spheroid models to distinguish toxic effects of gold and poly-lactic acid nanoparticles to assess biocompatibility for brain drug delivery.and Models to Study Mosquito-Borne Flavivirus Neuropathogenesis, Prevention, and TreatmentAdvanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systemsToxicity, recovery, and resilience in a 3D dopaminergic neuronal in vitro model exposed to rotenoneAntidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model
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researcher ORCID id 0000-0002-1224-573X
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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David Pamies
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P106
P1153
35330281000
P21
P31
P496
0000-0002-1224-573X