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AhR-Mediated, Non-Genomic Modulation of IDO1 FunctionIndoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cellsAryl hydrocarbon receptor control of a disease tolerance defence pathwayForced IDO1 expression in dendritic cells restores immunoregulatory signalling in autoimmune diabetesThe p50 subunit of NF-κB orchestrates dendritic cell lifespan and activation of adaptive immunity.Stem cells from human amniotic fluid exert immunoregulatory function via secreted indoleamine 2,3-dioxygenase1.A defect in tryptophan catabolism impairs tolerance in nonobese diabetic miceToward the identification of a tolerogenic signature in IDO-competent dendritic cells.Melanoma-Derived Wnt5a Promotes Local Dendritic-Cell Expression of IDO and Immunotolerance: Opportunities for Pharmacologic Enhancement of ImmunotherapyIndoleamine 2,3-dioxygenase 1 (IDO1) is up-regulated in thyroid carcinoma and drives the development of an immunosuppressant tumor microenvironment.LPS-conditioned dendritic cells confer endotoxin tolerance contingent on tryptophan catabolism.Ligand and cytokine dependence of the immunosuppressive pathway of tryptophan catabolism in plasmacytoid dendritic cells.Circulating levels of IL-10 are critically related to growth and rejection patterns of murine mastocytoma cells.CTLA-4-Ig regulates tryptophan catabolism in vivo.Modulation of tryptophan catabolism by regulatory T cells.CD28 induces immunostimulatory signals in dendritic cells via CD80 and CD86.High doses of CpG oligodeoxynucleotides stimulate a tolerogenic TLR9-TRIF pathway.CD40 ligation prevents onset of tolerogenic properties in human dendritic cells treated with CTLA-4-Ig.Enhanced tryptophan catabolism in the absence of the molecular adapter DAP12.Immunosuppression via tryptophan catabolism: the role of kynurenine pathway enzymesIL-22 is produced by γC-independent CD25+ CCR6+ innate murine spleen cells upon inflammatory stimuli and contributes to LPS-induced lethalityA GpC-Rich Oligonucleotide Acts on Plasmacytoid Dendritic Cells To Promote Immune SuppressionReverse signaling through GITR ligand enables dexamethasone to activate IDO in allergyTryptophan catabolism generates autoimmune-preventive regulatory T cellsIL-12 INDUCES SDS-STABLE CLASS II αβ DIMERS IN MURINE DENDRITIC CELLSImmunogenicity of tumor peptides: importance of peptide length and stability of peptide/MHC class II complexIL-12 Acts Directly on DC to Promote Nuclear Localization of NF-κB and Primes DC for IL-12 ProductionCytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γLoss of IDO1 Expression From Human Pancreatic β-Cells Precedes Their Destruction During the Development of Type 1 DiabetesPositive allosteric modulation of indoleamine 2,3-dioxygenase 1 restrains neuroinflammation
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հետազոտող
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Ciriana Orabona
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Ciriana Orabona
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Ciriana Orabona
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Ciriana Orabona
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