about
CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesisAfter double-strand break induction by UV-A, homologous recombination and nonhomologous end joining cooperate at the same DSB if both systems are availableComet assay measurements of DNA damage in cells by laser microbeams and trapping beams with wavelengths spanning a range of 308 nm to 1064 nm.Labelling quality and chromosome morphology after low temperature FISH analysed by scanning far-field and near-field optical microscopy.A direct view by immunofluorescent comet assay (IFCA) of DNA damage induced by nicking and cutting enzymes, ionizing (137)Cs radiation, UV-A laser microbeam irradiation and the radiomimetic drug bleomycin.Identification of the elementary structural units of the DNA damage response.Spatial association of homologous pericentric regions in human lymphocyte nuclei during repairSAMHD1 prevents autoimmunity by maintaining genome stability.Discrimination of Kinetic Models by a Combination of Microirradiation and Fluorescence Photobleaching.Generation of an alpaca-derived nanobody recognizing γ-H2AXUVA-induced DNA double-strand breaks result from the repair of clustered oxidative DNA damages.UV-A breakage sensitivity of human chromosomes as measured by COMET-FISH depends on gene density and not on the chromosome size.Introducing a true internal standard for the Comet assay to minimize intra- and inter-experiment variability in measures of DNA damage and repair.UVA radiation causes DNA strand breaks, chromosomal aberrations and tumorigenic transformation in HaCaT skin keratinocytes.Assessment of DNA damage in target tumor cells after thermoablation in mice.Gene repositioning within the cell nucleus is not random and is determined by its genomic neighborhood.UVA-induced apoptosis studied by the new apo/necro-Comet-assay which distinguishes viable, apoptotic and necrotic cells.Comet-FISH using peptide nucleic acid probes detects telomeric repeats in DNA damaged by bleomycin and mitomycin C proportional to general DNA damageNear-field scanning optical microscopy in cell biology and cytogeneticsAltered spatio-temporal dynamics of RNase H2 complex assembly at replication and repair sites in Aicardi-Goutières syndrome
P50
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P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
研究者
@zh
name
Alexander Rapp
@ast
Alexander Rapp
@en
Alexander Rapp
@es
Alexander Rapp
@nl
type
label
Alexander Rapp
@ast
Alexander Rapp
@en
Alexander Rapp
@es
Alexander Rapp
@nl
prefLabel
Alexander Rapp
@ast
Alexander Rapp
@en
Alexander Rapp
@es
Alexander Rapp
@nl
P106
P31
P496
0000-0001-9108-3929