Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
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Alterations of the intracellular peptidome in response to the proteasome inhibitor bortezomibAlternative Antigen Processing for MHC Class I: Multiple Roads Lead to RomeMHC class I antigen processing and presenting machinery: organization, function, and defects in tumor cellsMechanisms of HIV protein degradation into epitopes: implications for vaccine designThe origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01Critical roles of nardilysin in the maintenance of body temperature homoeostasisRedox modulation of thimet oligopeptidase activity by hydrogen peroxideHigh-frequency vaccine-induced CD8⁺ T cells specific for an epitope naturally processed during infection with Mycobacterium tuberculosis do not confer protectionExpression of THOP1 and its relationship to prognosis in non-small cell lung cancer.Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development.Serpinb9 (Spi6)-deficient mice are impaired in dendritic cell-mediated antigen cross-presentation.The cysteine-rich protein thimet oligopeptidase as a model of the structural requirements for S-glutathiolation and oxidative oligomerization.Concerted in vitro trimming of viral HLA-B27-restricted ligands by human ERAP1 and ERAP2 aminopeptidases.No major role for insulin-degrading enzyme in antigen presentation by MHC molecules.Cross-presentation of synthetic long peptides by human dendritic cells: a process dependent on ERAD component p97/VCP but Not sec61 and/or Derlin-1.An evolutionary analysis of antigen processing and presentation across different timescales reveals pervasive selection.The carboxypeptidase ACE shapes the MHC class I peptide repertoireIdentification and characterization of nardilysin as a novel dimethyl H3K4-binding protein involved in transcriptional regulation.The role of insulin-regulated aminopeptidase in MHC class I antigen presentation.Beyond HLA-A*0201: new HLA-transgenic nonobese diabetic mouse models of type 1 diabetes identify the insulin C-peptide as a rich source of CD8+ T cell epitopes.Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes.ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides.Peptidases released by necrotic cells control CD8+ T cell cross-priming.The Aeromonas salmonicida subsp. salmonicida exoproteome: determination of the complete repertoire of Type-Three Secretion System effectors and identification of other virulence factors.HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification.Providing ligands for MHC class I molecules.Post-proteasomal and proteasome-independent generation of MHC class I ligands.Running the gauntlet: from peptide generation to antigen presentation by MHC class I.Aeromonas salmonicida subsp. salmonicida in the light of its type-three secretion systemImmunogenicity of necrotic cell death.Proteasome subtypes and regulators in the processing of antigenic peptides presented by class I molecules of the major histocompatibility complex.A therapeutic T cell receptor mimic antibody targets tumor-associated PRAME peptide/HLA-I antigens.Allele-dependent processing pathways generate the endogenous human leukocyte antigen (HLA) class I peptide repertoire in transporters associated with antigen processing (TAP)-deficient cells.Different antigen-processing activities in dendritic cells, macrophages, and monocytes lead to uneven production of HIV epitopes and affect CTL recognition.The human leukocyte antigen-presented ligandome of B lymphocytes.Using protease inhibitors in antigen presentation assays.Human Tumor Antigens and Cancer Immunotherapy.Role of peptide processing predictions in T cell epitope identification: contribution of different prediction programs.Concerted antigen processing of a short viral antigen by human caspase-5 and -10.Characterization of a proteasome and TAP-independent presentation of intracellular epitopes by HLA-B27 molecules
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Antigen processing by nardilysin and thimet oligopeptidase generates cytotoxic T cell epitopes
description
article
@en
im Dezember 2010 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2010
@uk
name
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@en
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@nl
type
label
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@en
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@nl
prefLabel
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@en
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@nl
P2093
P2860
P50
P356
P1433
P1476
Antigen processing by nardilys ...... ates cytotoxic T cell epitopes
@en
P2093
Annette Paschen
Arend Mulder
Arnoud de Ru
Birgitta Tomkinson
Cornelis J M Melief
David W Rodgers
Ferry Ossendorp
Hermen S Overkleeft
Ilias I N Doxiadis
Jan H Kessler
P2860
P2888
P356
10.1038/NI.1974
P407
P577
2010-12-12T00:00:00Z
P6179
1033675093