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Ramipril inhibits AGE-RAGE-induced matrix metalloproteinase-2 activation in experimental diabetic nephropathyModulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy.Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs.RAGE-induced cytosolic ROS promote mitochondrial superoxide generation in diabetes.A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through disparate therapeutic approaches?Coming full circle in diabetes mellitus: from complications to initiation.Impairment of Liver Glycogen Storage in the db/db Animal Model of Type 2 Diabetes: A Potential Target for Future Therapeutics?Mapping time-course mitochondrial adaptations in the kidney in experimental diabetes.Deficiency in Apoptosis-Inducing Factor Recapitulates Chronic Kidney Disease via Aberrant Mitochondrial Homeostasis.Disparate effects on renal and oxidative parameters following RAGE deletion, AGE accumulation inhibition, or dietary AGE control in experimental diabetic nephropathy.Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content.RAGE Deletion Confers Renoprotection by Reducing Responsiveness to Transforming Growth Factor-β and Increasing Resistance to Apoptosis.Maternal inheritance of BDNF deletion, with phenotype of obesity and developmental delay in mother and child.Targeted reduction of advanced glycation improves renal function in obesityA rapid extraction method for glycogen from formalin-fixed liverObesity-induced renal impairment is exacerbated in interleukin-6-knockout miceUbiquinone (coenzyme Q10) prevents renal mitochondrial dysfunction in an experimental model of type 2 diabetesSerum IGFBP-2 levels are associated with reduced insulin sensitivity in obese childrenSex and puberty-related differences in metabolomic profiles associated with adiposity measures in youth with obesityPsychosocial measures and weight change in a clinical paediatric population with obesityNeighbourhood socioeconomic circumstances, adiposity and cardiometabolic risk measures in children with severe obesity
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description
researcher ORCID ID = 0000-0003-0028-873X
@en
wetenschapper
@nl
name
Brooke E Harcourt
@ast
Brooke E Harcourt
@en
Brooke E Harcourt
@es
Brooke E Harcourt
@nl
type
label
Brooke E Harcourt
@ast
Brooke E Harcourt
@en
Brooke E Harcourt
@es
Brooke E Harcourt
@nl
prefLabel
Brooke E Harcourt
@ast
Brooke E Harcourt
@en
Brooke E Harcourt
@es
Brooke E Harcourt
@nl
P108
P106
P1153
25027581900
P31
P496
0000-0003-0028-873X