about
Synthesis and pharmacological evaluation of functionalized isoindolinones on GABA-activated chloride currents in rat cerebellum granule cells in culture.Design of chiral urea-quaternary ammonium salt hybrid catalysts for asymmetric reactions of glycine Schiff basesDesign of inhibitors of influenza virus membrane fusion: synthesis, structure-activity relationship and in vitro antiviral activity of a novel indole series.Cyclohexa-2,5-diene-1,4-dione-based antiproliferative agents: design, synthesis, and cytotoxic evaluation.Discovery of novel multi-target indole-based derivatives as potent and selective inhibitors of chikungunya virus replication.Design, synthesis, biophysical and biological studies of trisubstituted naphthalimides as G-quadruplex ligands.2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone derivatives as new anti Flaviviridae inhibitors.Bifunctional phase-transfer catalysis in the asymmetric synthesis of biologically active isoindolinones.Synthesis of new chiral 2,2'-bipyridine ligands and their application in copper-catalyzed asymmetric allylic oxidation and cyclopropanation.Design, synthesis and biological evaluation of novel bicyclo[1.1.1]pentane-based omega-acidic amino acids as glutamate receptors ligands.Model-averaging of ab initio spectra for the absolute configuration assignment via vibrational circular dichroism.Combined electrochemical/chemical methods for the synthesis and the molecular diversifying of isoindolinone-based heterocyclic scaffolds.Determination of the absolute configuration of a novel tetrasubstituted isoindolinone by vibrational circular dichroism.Exploring the role of chloro and methyl substitutions in 2-phenylthiomethyl-benzoindole derivatives for 5-LOX enzyme inhibitionAsymmetric tandem hemiaminal-heterocyclization-aza-Mannich reaction of 2-formylbenzonitriles and amines using chiral phase transfer catalysis: an experimental and theoretical studyHighly diastereo- and enantioselective organocatalytic synthesis of new heterocyclic hybrids isoindolinone-imidate and isoindolinone-phthalide3-Carboxylate-Substituted Isoindolinones in K2CO3-Catalyzed Michael ReactionsIsoindolinones as Michael Donors under Phase Transfer Catalysis: Enantioselective Synthesis of Phthalimidines Containing a Tetrasubstituted Carbon StereocenterOrganocatalytic asymmetric synthesis of highly functionalized pyrrolizidines via cascade Michael/hemi-aminalization reactions of isoindolinonesQuick and easy access to N-Mannich bases of 1-isoindolinones by catalytic electroactivation of primary and secondary amines and tandem reaction with 2-formylbenzonitrilesCascade reactions of glycine Schiff bases and chiral phase transfer catalysts in the synthesis of α-amino acids 3-substituted phthalides or isoindolinonesNew chelating agents for Cu(II), Fe(III), Al(III), and Zn(II) based on β-diketonate-3-substituted phthalide (isobenzofuranone) and isoindolinoneOrganocatalysts and sequential asymmetric cascade reactions in the synthesis of functionalized isoindolinones and benzoindolizidinonesActive methylene compounds in a very effective approach to 3-substituted isobenzofuranones through tandem aldol/lactonization reactionsActive Methylene Compounds in the Synthesis of 3-substituted Isobenzofuranones, Isoindolinones and Related CompoundsElectrochemically Initiated Tandem and Sequential Conjugate Addition Processes: One-Pot Synthesis of Diverse Functionalized IsoindolinonesSynthesis and Reactivity of the 3-Substituted Isoindolinone Framework to Assemble Highly Functionalized Related StructuresThe Aldol Reactions of Active Methylene CompoundsThe first organocatalytic asymmetric synthesis of 3-substituted isoindolinonesMulti-component, regio-selective aldol addition of β-ketoesters to aldehydes: scope and applicationsTrimethylchlorosilane and Silicon Tetrachloride in Two Novel Methodologies for the Efficient and Mild Aldol Addition of β-Keto Esters and Malonates to AldehydesFurther studies on ethyl 5-hydroxy-indole-3-carboxylate scaffold: Design, synthesis and evaluation of 2-phenylthiomethyl-indole derivatives as efficient inhibitors of human 5-lipoxygenaseChiral sulfoxides as activators of allyl trichlorosilanes in the stereoselective allylation of aldehydesChiral sulfoxides in the enantioselective allylation of aldehydes with allyltrichlorosilane: a kinetic studyMetal-Free Air Oxidation in a Convenient Cascade Approach for the Access to Isoquinoline-1,3,4(2H)-trionesChiral Phase Transfer Catalysis in the Asymmetric Synthesis of a 3,3-Disubstituted Isoindolinone and Determination of Its Absolute Configuration by VCD Spectroscopy
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description
researcher ORCID ID = 0000-0003-4921-4766
@en
wetenschapper
@nl
name
Antonio Massa
@ast
Antonio Massa
@en
Antonio Massa
@es
Antonio Massa
@nl
type
label
Antonio Massa
@ast
Antonio Massa
@en
Antonio Massa
@es
Antonio Massa
@nl
prefLabel
Antonio Massa
@ast
Antonio Massa
@en
Antonio Massa
@es
Antonio Massa
@nl
P106
P1153
35237534700
P21
P31
P496
0000-0003-4921-4766