Analysis of Fluoromethyl Group Chirality Establishes a Common Stereochemical Course for the Enolpyruvyl Transfers Catalyzed by EPSP Synthase and UDP-GlcNAc Enolpyruvyl Transferase†
about
Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detailA new view of the mechanisms of UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) and 5-enolpyruvylshikimate-3-phosphate synthase (AroA) derived from X-ray structures of their tetrahedral reaction intermediate statesEvidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release.Prospects for new antibiotics: a molecule-centered perspective.Mechanism-based inhibition of enzyme I of the Escherichia coli phosphotransferase system. Cysteine 502 is an essential residue.Amphipathic property of free thiol group contributes to an increase in the catalytic efficiency of carboxypeptidase Y.Synthesis of phosphoenol pyruvate (PEP) analogues and evaluation as inhibitors of PEP-utilizing enzymes.
P2860
Q24628981-7E605CB7-F732-4EC8-87F7-359A62E74880Q27642065-3093B778-7B2B-4630-BA29-E7D4359F53F3Q37866109-973FD4C0-8203-4849-926F-7AADBAA596D1Q38113689-BAA931A1-4167-4C7B-ADCC-4674946422FBQ43821664-079DD117-E594-4230-946C-D164E22D9755Q44041405-629184A9-C989-4E4D-9FB9-69C7CFFC7142Q44041407-A16DD14A-5F62-4871-9F96-809ECB655AA1
P2860
Analysis of Fluoromethyl Group Chirality Establishes a Common Stereochemical Course for the Enolpyruvyl Transfers Catalyzed by EPSP Synthase and UDP-GlcNAc Enolpyruvyl Transferase†
description
article
@en
im April 1996 veröffentlicher wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 1996
@uk
name
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@en
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@nl
type
label
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@en
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@nl
prefLabel
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@en
Analysis of Fluoromethyl Group ...... lcNAc Enolpyruvyl Transferase†
@nl
P2093
P356
P1433
P1476
Analysis of fluoromethyl group ...... GlcNAc enolpyruvyl transferase
@en
P2093
P304
P356
10.1021/BI952978S
P407
P577
1996-04-01T00:00:00Z