about
Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid SystemIdentification and quantification of a new family of peptide endocannabinoids (Pepcans) showing negative allosteric modulation at CB1 receptors.Functionally Optimized Neuritogenic Farinosone C Analogs: SAR-Study and Investigations on Their Mode of ActionCorrelating FAAH and anandamide cellular uptake inhibition using N-alkylcarbamate inhibitors: from ultrapotent to hyperpotent.Chemical probes to potently and selectively inhibit endocannabinoid cellular reuptake.Splice variants of activation induced deaminase (AID) do not affect the efficiency of class switch recombination in murine CH12F3 cells.Elevated levels of endocannabinoids in chronic hepatitis C may modulate cellular immune response and hepatic stellate cell activation.4'-O-methylhonokiol increases levels of 2-arachidonoyl glycerol in mouse brain via selective inhibition of its COX-2-mediated oxygenation.Evidence for bidirectional endocannabinoid transport across cell membranesThe antinociceptive triterpene β-amyrin inhibits 2-arachidonoylglycerol (2-AG) hydrolysis without directly targeting cannabinoid receptors.Cytotoxic activity of polyacetylenes and polyenes isolated from roots of Echinacea pallida.Cannabinoid CB2 receptor ligand profiling reveals biased signalling and off-target activity.Synthetic Cannabinoid Receptor Agonists and Antagonists: Implication in CNS Disorders.Beyond the Direct Activation of Cannabinoid Receptors: New Strategies to Modulate the Endocannabinoid System in CNS-Related Diseases.Anticancer activity of anandamide in human cutaneous melanoma cells.Synthesis and cytotoxic activity of non-naturally substituted 4-oxycoumarin derivatives.Anti-proliferative activity of aguerin B and a new rare nor-guaianolide lactone isolated from the aerial parts of Centaurea deflexa.Cytotoxic activity and G1 cell cycle arrest of a Dienynone from Echinacea pallida.Modulation of P-glycoprotein activity by cannabinoid molecules in HK-2 renal cells.Cannabinoid derivatives induce cell death in pancreatic MIA PaCa-2 cells via a receptor-independent mechanism.Development of an HPLC/UV assay for the evaluation of inhibitors of human recombinant monoacylglycerol lipase.Pepcan-12 (RVD-hemopressin) is a CB2 receptor positive allosteric modulator constitutively secreted by adrenals and in liver upon tissue damage.Analysis of reptilian APOBEC1 suggests that RNA editing may not be its ancestral function.Reactions of CF3-enones with arenes under superelectrophilic activation: a pathway to trans-1,3-diaryl-1-CF3-indanes, new cannabinoid receptor ligands.Novel analogs of PSNCBAM-1 as allosteric modulators of cannabinoid CB1 receptor.Discovery of 1,5-Diphenylpyrazole-3-Carboxamide Derivatives as Potent, Reversible, and Selective Monoacylglycerol Lipase (MAGL) Inhibitors.β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice.Synthesis and pharmacological evaluation of new biphenylic derivatives as CB2 receptor ligands.4-O'-methylhonokiol protects from alcohol/carbon tetrachloride-induced liver injury in mice.Biological evaluation of pyridone alkaloids on the endocannabinoid system.Synergistic immunomopharmacological effects of N-alkylamides in Echinacea purpurea herbal extracts.Sequence characterized amplified region (SCAR) analysis on DNA from the three medicinal Echinacea species.The Endocannabinoid Reuptake Inhibitor WOBE437 Is Orally Bioavailable and Exerts Indirect Polypharmacological Effects via Different Endocannabinoid Receptors.Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairmentsUncovering the psychoactivity of a cannabinoid from liverworts associated with a legal highCytotoxic effects of Echinacea root hexanic extracts on human cancer cell linesDiscovery of long-chain salicylketoxime derivatives as monoacylglycerol lipase (MAGL) inhibitorsPolypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid systemAssay of Endocannabinoid UptakeEther-Substituted Group 4 Metallocene Complexes: Cytostatic Effects and Applications in Ethylene Polymerization
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description
researcher ORCID ID = 0000-0001-9593-636X
@en
wetenschapper
@nl
name
Andrea Chicca
@ast
Andrea Chicca
@en
Andrea Chicca
@es
Andrea Chicca
@nl
type
label
Andrea Chicca
@ast
Andrea Chicca
@en
Andrea Chicca
@es
Andrea Chicca
@nl
prefLabel
Andrea Chicca
@ast
Andrea Chicca
@en
Andrea Chicca
@es
Andrea Chicca
@nl
P106
P1153
15839206200
P21
P31
P496
0000-0001-9593-636X