about
Human butyrylcholinesterase produced in insect cells: huprine-based affinity purification and crystal structureCrystal structure of the vaccinia virus DNA polymerase holoenzyme subunit D4 in complex with the A20 N-terminal domainStructure-based development of nitroxoline derivatives as potential multifunctional anti-Alzheimer agentsDiscovery and Structure-Activity Relationships of a Highly Selective Butyrylcholinesterase Inhibitor by Structure-Based Virtual ScreeningGenetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasisCrystallization and preliminary X-ray diffraction data for the aconitase form of human iron-regulatory protein 1.An EPR/HYSCORE, Mössbauer, and resonance Raman study of the hydrogenase maturation enzyme HydF: a model for N-coordination to [4Fe-4S] clusters.Development of an in-vivo active reversible butyrylcholinesterase inhibitor.Progress in the development of enzyme-based nerve agent bioscavengers.N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer's agents.Structural analysis of point mutations at the Vaccinia virus A20/D4 interface.Interactions between doxorubicin and the human iron regulatory system.Organophosphate hydrolases as catalytic bioscavengers of organophosphorus nerve agents.Bacterial Expression of Human Butyrylcholinesterase as a Tool for Nerve Agent Bioscavengers Development.The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study.Interaction of Ubinuclein-1, a nuclear and adhesion junction protein, with the 14-3-3 epsilon protein in epithelial cells: Implication of the PKA pathwayHuman Cytoplasmic Aconitase (Iron Regulatory Protein 1) Is Converted into Its [3Fe-4S] Form by Hydrogen Peroxidein Vitrobut Is Not Activated for Iron-responsive Element BindingPurification of recombinant human butyrylcholinesterase on Hupresin®Three conserved histidine residues contribute to mitochondrial iron transport through mitoferrinsStructural changes associated with switching activities of human iron regulatory protein 1The Saccharomyces cerevisiae ADP/ATP carrier-iso 1 cytochrome c fusion protein: one-step purification and functional analysis in vitroMulti-target-directed ligands for treating Alzheimer's disease: Butyrylcholinesterase inhibitors displaying antioxidant and neuroprotective activitiesNovel tacrine-tryptophan hybrids: Multi-target directed ligands as potential treatment for Alzheimer's diseaseTryptophan-derived butyrylcholinesterase inhibitors as promising leads against Alzheimer's disease
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description
researcher ORCID ID = 0000-0001-9219-1032
@en
wetenschapper
@nl
name
Xavier Brazzolotto
@ast
Xavier Brazzolotto
@en
Xavier Brazzolotto
@es
Xavier Brazzolotto
@nl
type
label
Xavier Brazzolotto
@ast
Xavier Brazzolotto
@en
Xavier Brazzolotto
@es
Xavier Brazzolotto
@nl
prefLabel
Xavier Brazzolotto
@ast
Xavier Brazzolotto
@en
Xavier Brazzolotto
@es
Xavier Brazzolotto
@nl
P106
P21
P31
P496
0000-0001-9219-1032