about
Semi-synthesis of labeled proteins for spectroscopic applicationsCrystal structure of an S-formylglutathione hydrolase from Pseudoalteromonas haloplanktis TAC125Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivoSemisynthesis of a segmental isotopically labeled protein splicing precursor: NMR evidence for an unusual peptide bond at the N-extein-intein junction.γ Sulphate PNA (PNA S): highly selective DNA binding molecule showing promising antigene activity.New perspectives for natural antimicrobial peptides: application as antinflammatory drugs in a murine modelNew peptide nucleic acid analogues: synthesis and applications.Circular Dichroism studies on the interactions of antimicrobial peptides with bacterial cells.Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity.Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells.gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions.PNA zipper as a dimerization tool: development of a bZip mimic.Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites.Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NF-kappaB transcription factors.Highly efficient DNA-free gene disruption in the agricultural pest Ceratitis capitata by CRISPR-Cas9 ribonucleoprotein complexes.Functional binding surface of a β-hairpin VEGF receptor targeting peptide determined by NMR spectroscopy in living cells.Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis.In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with 99mTc-tricarbonyl.Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles.Antimicrobial peptides from plants: stabilization of the γ core of a tomato defensin by intramolecular disulfide bond.Crystallization and preliminary X-ray diffraction studies of a D-lysine-based chiral PNA-DNA duplex.Activity of anchored human matrix metalloproteinase-1 catalytic domain on Au (111) surfaces monitored by ESI-MS.Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide.Plant-to-plant communication triggered by systemin primes anti-herbivore resistance in tomato.Conformational stabilization of a β-hairpin through a triazole-tryptophan interaction.Self-assembling of Fmoc-GC Peptide Nucleic Acid dimers into highly fluorescent aggregates.Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2.Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine.Structural basis of a temporin 1b analogue antimicrobial activity against Gram negative bacteria determined by CD and NMR techniques in cellular environment.Complexation to Cationic Microspheres of Double-Stranded Peptide Nucleic Acid-DNA Chimeras Exhibiting Decoy ActivityBioinorganic aspects of angiogenesis.Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient DeliveryCrystal-state conformation of C?,?-dialkylated peptides containing chiral ?-homo-residuesPeptides from Royal Jelly: studies on the antimicrobial activity of jelleins, jelleins analogs and synergy with temporinsDesign, structural and functional characterization of a Temporin-1b analog active against Gram-negative bacteriaβ-Hairpin stabilization through an interstrand triazole bridgeSemisynthesis of dimeric proteins by expressed protein ligationEffect of Acylation on the Antimicrobial Activity of Temporin B AnaloguesFluorescence and Morphology of Self-Assembled Nucleobases and Their Diphenylalanine Hybrid AggregatesCoordination of a bis-histidine-oligopeptide to Re(i) and Ga(iii) in aqueous solution
P50
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P50
description
researcher ORCID ID = 0000-0002-7609-4061
@en
wetenschapper
@nl
name
Alessandra Romanelli
@ast
Alessandra Romanelli
@en
Alessandra Romanelli
@es
Alessandra Romanelli
@nl
type
label
Alessandra Romanelli
@ast
Alessandra Romanelli
@en
Alessandra Romanelli
@es
Alessandra Romanelli
@nl
prefLabel
Alessandra Romanelli
@ast
Alessandra Romanelli
@en
Alessandra Romanelli
@es
Alessandra Romanelli
@nl
P106
P1153
7006218629
P21
P31
P496
0000-0002-7609-4061