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The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cellsNa+/H+ exchanger regulatory factor 1 overexpression-dependent increase of cytoskeleton organization is fundamental in the rescue of F508del cystic fibrosis transmembrane conductance regulator in human airway CFBE41o- cellsEvaluation of genome-wide expression profiles of blood and sputum neutrophils in cystic fibrosis patients before and after antibiotic therapy.CFTR regulation in human airway epithelial cells requires integrity of the actin cytoskeleton and compartmentalized cAMP and PKA activity.Cftr gene targeting in mouse embryonic stem cells mediated by Small Fragment Homologous Replacement (SFHR)Reciprocal protein kinase A regulatory interactions between cystic fibrosis transmembrane conductance regulator and Na+/H+ exchanger isoform 3 in a renal polarized epithelial cell model.Characterization of mitochondrial function in cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function.Trimethylangelicin promotes the functional rescue of mutant F508del CFTR protein in cystic fibrosis airway cells.Protease activity at invadopodial focal digestive areas is dependent on NHE1-driven acidic pHe.NHERF1 and CFTR restore tight junction organisation and function in cystic fibrosis airway epithelial cells: role of ezrin and the RhoA/ROCK pathway.Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function.Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1.NHE3 inhibits PKA-dependent functional expression of CFTR by NHERF2 PDZ interactions.Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines.Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells.Extracellular adenine nucleotides regulate Na+/H+ exchanger NHE3 activity in A6-NHE3 transfectants by a cAMP/PKA-dependent mechanism.Activation of A(3) adenosine receptor induces calcium entry and chloride secretion in A(6) cells.Goblet Cell Hyperplasia Requires High Bicarbonate Transport To Support Mucin Release.Increase in interleukin-8 production from circulating neutrophils upon antibiotic therapy in cystic fibrosis patients.Effects of beta-endorphin and Naloxone on in vitro maturation of bovine oocytes.Expression and localization of the mu-opioid receptor (MOR) in the equine cumulus-oocyte complex and its involvement in the seasonal regulation of oocyte meiotic competence.The extracellular calcium-sensing receptor is expressed in the cumulus-oocyte complex in mammals and modulates oocyte meiotic maturation.Antibiotic therapy affects functional behaviour in cystic fibrosis blood mononuclear cells.Correctors of mutant CFTR enhance subcortical cAMP-PKA signaling through modulating ezrin phosphorylation and cytoskeleton organization.Rescue of murine silica-induced lung injury and fibrosis by human embryonic stem cellsStimulation of β2-adrenergic receptor increases CFTR function and decreases ATP levels in murine hematopoietic stem/progenitor cells
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-3950-9405
@en
name
Lorenzo Guerra
@ast
Lorenzo Guerra
@en
Lorenzo Guerra
@es
Lorenzo Guerra
@nl
type
label
Lorenzo Guerra
@ast
Lorenzo Guerra
@en
Lorenzo Guerra
@es
Lorenzo Guerra
@nl
prefLabel
Lorenzo Guerra
@ast
Lorenzo Guerra
@en
Lorenzo Guerra
@es
Lorenzo Guerra
@nl
P106
P1153
7103192569
P21
P31
P496
0000-0003-3950-9405