Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration
about
Guidelines for the use and interpretation of assays for monitoring autophagySkeletal muscle laminin and MDC1A: pathogenesis and treatment strategies.AMBRA1 is able to induce mitophagy via LC3 binding, regardless of PARKIN and p62/SQSTM1Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial functionPhysical exercise stimulates autophagy in normal skeletal muscles but is detrimental for collagen VI-deficient musclesActivation of autophagy is required for muscle homeostasis during physical exerciseThe rise of mitochondria in medicineSIRT1: A Novel Target for the Treatment of Muscular DystrophiesThe beneficial role of proteolysis in skeletal muscle growth and stress adaptationOxidative Stress-Mediated Skeletal Muscle Degeneration: Molecules, Mechanisms, and TherapiesMitochondrial Quality Control and Muscle Mass MaintenanceRole of Inflammation in Muscle Homeostasis and MyogenesisMitophagy: mechanisms, pathophysiological roles, and analysisSkeletal muscle autophagy: a new metabolic regulatorMitochondria and the autophagy-inflammation-cell death axis in organismal agingCollagen VI and hyaluronan: the common role in breast cancerCellular and molecular mechanisms of muscle atrophyRole of autophagy in COPD skeletal muscle dysfunctionA TALEN-Exon Skipping Design for a Bethlem Myopathy Model in ZebrafishIntestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary RestrictionDifferential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell TransplantationDisrupted autophagy undermines skeletal muscle adaptation and integrityInsights into the key roles of proteoglycans in breast cancer biology and translational medicineHanging on for the ride: adhesion to the extracellular matrix mediates cellular responses in skeletal muscle morphogenesis and diseasePathophysiological concepts in the congenital myopathies: blurring the boundaries, sharpening the focusRegulation of autophagy by Beclin 1 in the heartX-linked myopathy with excessive autophagy: a failure of self-eatingMitochondria-ros crosstalk in the control of cell death and agingMitochondrial fission, fusion, and stressMutations in INPP5K, Encoding a Phosphoinositide 5-Phosphatase, Cause Congenital Muscular Dystrophy with Cataracts and Mild Cognitive ImpairmentThe induction of autophagy by mechanical stress.Rapamycin nanoparticles target defective autophagy in muscular dystrophy to enhance both strength and cardiac functionCholesterol-mediated activation of acid sphingomyelinase disrupts autophagy in the retinal pigment epitheliumDegeneration of neuromuscular junction in age and dystrophy.Atrogin-1 deficiency promotes cardiomyopathy and premature death via impaired autophagy.Exercise-induced skeletal muscle remodeling and metabolic adaptation: redox signaling and role of autophagy.Human adipose-derived stem cell transplantation as a potential therapy for collagen VI-related congenital muscular dystrophyAge-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence.Haptoglobin is required to prevent oxidative stress and muscle atrophy.Allele-specific Gene Silencing of Mutant mRNA Restores Cellular Function in Ullrich Congenital Muscular Dystrophy Fibroblasts.
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P2860
Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration
description
im Oktober 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 31 October 2010
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в жовтні 2010
@uk
name
Autophagy is defective in coll ...... rescues myofiber degeneration
@en
Autophagy is defective in coll ...... rescues myofiber degeneration
@nl
type
label
Autophagy is defective in coll ...... rescues myofiber degeneration
@en
Autophagy is defective in coll ...... rescues myofiber degeneration
@nl
prefLabel
Autophagy is defective in coll ...... rescues myofiber degeneration
@en
Autophagy is defective in coll ...... rescues myofiber degeneration
@nl
P2093
P50
P356
P1433
P1476
Autophagy is defective in coll ...... rescues myofiber degeneration
@en
P2093
Alessia Angelin
Anna Urciuolo
Enrico Bertaggia
Luisa Coletto
Marco Sandri
Nadir M Maraldi
Paolo Bonaldo
Paolo Grumati
Patrizia Sabatelli
Tania Tiepolo
P2888
P304
P356
10.1038/NM.2247
P407
P577
2010-10-31T00:00:00Z
P6179
1022544032