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RhoG regulates endothelial apical cup assembly downstream from ICAM1 engagement and is involved in leukocyte trans-endothelial migration.Crossing the Vascular Wall: Common and Unique Mechanisms Exploited by Different Leukocyte Subsets during ExtravasationRho GAPs and GEFs: controling switches in endothelial cell adhesionThe guanine-nucleotide exchange factor SGEF plays a crucial role in the formation of atherosclerosisInside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endotheliumF-actin-rich contractile endothelial pores prevent vascular leakage during leukocyte diapedesis through local RhoA signallingThe N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion.The Rho-GEF Trio regulates a novel pro-inflammatory pathway through the transcription factor Ets2.The Rho-guanine nucleotide exchange factor Trio controls leukocyte transendothelial migration by promoting docking structure formation.Trichuris suis induces human non-classical patrolling monocytes via the mannose receptor and PKC: implications for multiple sclerosis.Filamin B mediates ICAM-1-driven leukocyte transendothelial migration.Diabetes mellitus induces bone marrow microangiopathy.Endothelial junction regulation: a prerequisite for leukocytes crossing the vessel wall.Sphingosine-1-phosphate receptor 3 mediates sphingosine-1-phosphate induced release of weibel-palade bodies from endothelial cells.Real-time imaging of endothelial cell-cell junctions during neutrophil transmigration under physiological flow.Two CGD Families with a Hypomorphic Mutation in the Activation Domain of p67(phox)Plasminogen Activator Inhibitor-1 Controls Vascular Integrity by Regulating VE-Cadherin TraffickingLeukocytes Crossing the Endothelium: A Matter of Communication.Trading spaces: Rap, Rac, and Rho as architects of transendothelial migration.The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylationRecruitment of Immune Cells into Inflamed Tissues: Consequences for Endothelial Barrier Integrity and Tissue Functionality.A rare variant in MCF2L identified using exclusion linkage in a pedigree with premature atherosclerosisEndothelial signaling by Ig-like cell adhesion molecules.Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study.The many faces of the guanine-nucleotide exchange factor trio.Rho-GTPase signaling in leukocyte extravasation: an endothelial point of view.Oxidized Phospholipids on Lipoprotein(a) Elicit Arterial Wall Inflammation and an Inflammatory Monocyte Response in Humans.The Ins and Outs of Small GTPase Rac1 in the Vasculature.Flow-induced endothelial cell alignment requires the RhoGEF Trio as a scaffold protein to polarize active Rac1 distribution.Acid Sphingomyelinase-Derived Ceramide Regulates ICAM-1 Function during T Cell Transmigration across Brain Endothelial Cells.Leukocyte transendothelial migration: A local affair.P-glycoprotein regulates trafficking of CD8(+) T cells to the brain parenchyma.Leukocyte Breaching of Endothelial Barriers: The Actin Link.ICAM-1 clustering on endothelial cells recruits VCAM-1Annexin A2 Limits Neutrophil Transendothelial Migration by Organizing the Spatial Distribution of ICAM-1.A local VE-cadherin and Trio-based signaling complex stabilizes endothelial junctions through Rac1.Erratum to: Unexpected arterial wall and cellular inflammation in patients with rheumatoid arthritis in remission using biological therapy: a cross-sectional study.The presence of alpha-catenin in the VE-cadherin complex is required for efficient transendothelial migration of leukocytesA disintegrin and metalloprotease 10 is a novel mediator of vascular endothelial growth factor-induced endothelial cell function in angiogenesis and is associated with atherosclerosis.Small Rho GTPase-mediated actin dynamics at endothelial adherens junctions.
P50
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P50
description
researcher ORCID ID = 0000-0003-0054-7949
@en
wetenschapper
@nl
name
Jaap D van Buul
@ast
Jaap D van Buul
@en
Jaap D van Buul
@nl
type
label
Jaap D van Buul
@ast
Jaap D van Buul
@en
Jaap D van Buul
@nl
prefLabel
Jaap D van Buul
@ast
Jaap D van Buul
@en
Jaap D van Buul
@nl
P106
P31
P496
0000-0003-0054-7949