Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1
about
Isolation and characterization of a novel plasma membrane protein, osteoblast induction factor (obif), associated with osteoblast differentiationMenin is required for bone morphogenetic protein 2- and transforming growth factor beta-regulated osteoblastic differentiation through interaction with Smads and Runx2FIAT represses ATF4-mediated transcription to regulate bone mass in transgenic miceMenin suppresses osteoblast differentiation by antagonizing the AP-1 factor, JunDDoubly truncated FosB isoform (Delta2DeltaFosB) induces osteosclerosis in transgenic mice and modulates expression and phosphorylation of Smads in osteoblasts independent of intrinsic AP-1 activityRegulation of gene expression in osteoblasts.Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defectsTranscription factor C/EBPbeta isoform ratio regulates osteoclastogenesis through MafBParathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor beta in osteoblastsFra-1 promotes growth and survival in RAS-transformed thyroid cells by controlling cyclin A transcriptionMultiple cis-elements mediate the transcriptional activation of human fra-1 by 12-O-tetradecanoylphorbol-13-acetate in bronchial epithelial cellsSmall molecule inhibitors targeting activator protein 1 (AP-1).Finding genes in the C2C12 osteogenic pathway by k-nearest-neighbor classification of expression data.RPL38, FOSL1, and UPP1 are predominantly expressed in the pancreatic ductal epithelium.Bones, genes and fractures: workshop on the genetics of osteoporosis: from basic to clinical research.Distinct functions of junD in cardiac hypertrophy and heart failureEssential role of RSK2 in c-Fos-dependent osteosarcoma development.Emerging roles of ATF2 and the dynamic AP1 network in cancer.siRNA knock-down of RANK signaling to control osteoclast-mediated bone resorption.Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic enhancer.Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation.Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biologyThe AP-1 transcription factor Fra1 inhibits follicular B cell differentiation into plasma cells.Fra-1/AP-1 transcription factor negatively regulates pulmonary fibrosis in vivo.Novel therapeutic targets in osteoporosis.Enhancement of Flow-Induced AP-1 Gene Expression by Cyclosporin A Requires NFAT-Independent Signaling in Bone Cells.Fra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.Mesenchymal progenitor self-renewal deficiency leads to age-dependent osteoporosis in Sca-1/Ly-6A null mice.Osteosclerosis owing to Notch gain of function is solely Rbpj-dependentControl of osteoblast function and regulation of bone mass.Signalling in osteoclasts and the role of Fos/AP1 proteins.BET inhibitors induce apoptosis through a MYC independent mechanism and synergise with CDK inhibitors to kill osteosarcoma cellsGene expression changes in human mesenchymal stem cells from patients with osteoporosis.Photodynamic activation as a molecular switch to promote osteoblast cell differentiation via AP-1 activationAdenoviral transfer of murine oncostatin M elicits periosteal bone apposition in knee joints of mice, despite synovial inflammation and up-regulated expression of interleukin-6 and receptor activator of nuclear factor-kappa B ligandOsteoprotegerin Regulates Pancreatic β-Cell Homeostasis upon Microbial InvasionStat1 functions as a cytoplasmic attenuator of Runx2 in the transcriptional program of osteoblast differentiation.Estrogen-induced expression of Fos-related antigen 1 (FRA-1) regulates uterine stromal differentiation and remodeling.Meteorin-Like Shows Unique Expression Pattern in Bone and Its Overexpression Inhibits Osteoblast Differentiation.Sensitivity of human lung adenocarcinoma cell lines to targeted inhibition of BET epigenetic signaling proteins
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P2860
Increased bone formation and osteosclerosis in mice overexpressing the transcription factor Fra-1
description
im September 2000 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2000
@uk
name
Increased bone formation and o ...... the transcription factor Fra-1
@en
Increased bone formation and o ...... the transcription factor Fra-1
@nl
type
label
Increased bone formation and o ...... the transcription factor Fra-1
@en
Increased bone formation and o ...... the transcription factor Fra-1
@nl
prefLabel
Increased bone formation and o ...... the transcription factor Fra-1
@en
Increased bone formation and o ...... the transcription factor Fra-1
@nl
P2093
P356
P1433
P1476
Increased bone formation and o ...... the transcription factor Fra-1
@en
P2093
Anton Wutz
Candace Elliott
Hanns Plenk
Jean-Pierre David
Wolfram Jochum
P2888
P304
P356
10.1038/79676
P407
P577
2000-09-01T00:00:00Z