Effective Utilization ofN2-Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases†
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Polyamines stimulate the formation of mutagenic 1,N2-propanodeoxyguanosine adducts from acetaldehydeLesion Bypass of N2-Ethylguanine by Human DNA Polymerase ιVersatility of Y-family Sulfolobus solfataricus DNA Polymerase Dpo4 in Translesion Synthesis Past Bulky N2-Alkylguanine AdductsStructure-Function Relationships in Miscoding by Sulfolobus solfataricus DNA Polymerase Dpo4: GUANINE N2,N2-DIMETHYL SUBSTITUTION PRODUCES INACTIVE AND MISCODING POLYMERASE COMPLEXESAcetaldehyde as an underestimated risk factor for cancer development: role of genetics in ethanol metabolismTargeting aldehyde dehydrogenase 2: new therapeutic opportunities.Mechanisms of alcohol-induced hepatocellular carcinoma.Alcohol and upper gastrointestinal tract cancer: the role of local acetaldehyde production.Acetaldehyde, microbes, and cancer of the digestive tract.Identification of an acetaldehyde adduct in human liver DNA and quantitation as N2-ethyldeoxyguanosineIncreased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.Risk factors and mechanisms of hepatocarcinogenesis with special emphasis on alcohol and oxidative stress.Translesional synthesis on a DNA template containing N2-methyl-2'-deoxyguanosine catalyzed by the Klenow fragment of Escherichia coli DNA polymerase IDifferential blocking effects of the acetaldehyde-derived DNA lesion N2-ethyl-2'-deoxyguanosine on transcription by multisubunit and single subunit RNA polymerasesChemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal.Enhancement of camptothecin-induced topoisomerase I cleavage complexes by the acetaldehyde adduct N2-ethyl-2'-deoxyguanosine.Vinyl acetate monomer (VAM) genotoxicity profile: relevance for carcinogenicity.Kinetic evidence for inefficient and error-prone bypass across bulky N2-guanine DNA adducts by human DNA polymerase iota.Analysis of the effect of bulk at N2-alkylguanine DNA adducts on catalytic efficiency and fidelity of the processive DNA polymerases bacteriophage T7 exonuclease- and HIV-1 reverse transcriptase.Molecular Mechanisms of Acetaldehyde-Mediated Carcinogenesis in Squamous Epithelium.Alcohol metabolism: role in toxicity and carcinogenesis.Alcohol-Derived Acetaldehyde Exposure in the Oral Cavity.
P2860
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P2860
Effective Utilization ofN2-Ethyl-2‘-deoxyguanosine Triphosphate during DNA Synthesis Catalyzed by Mammalian Replicative DNA Polymerases†
description
article
@en
im Januar 1999 veröffentlicher wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 1999
@uk
name
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@en
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@nl
type
label
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@en
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@nl
prefLabel
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@en
Effective Utilization ofN2-Eth ...... n Replicative DNA Polymerases†
@nl
P2093
P356
P1433
P1476
Effective utilization of N2-et ...... an replicative DNA polymerases
@en
P2093
Shibutani S
Terashima I
Yabushita H
P304
P356
10.1021/BI982134J
P407
P577
1999-01-01T00:00:00Z