Protective Immunity Against Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain After Vaccination with Genes Encoding the Amastigote Surface Protein-2 and Trans-Sialidase
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Relevance of the diversity among members of the Trypanosoma cruzi trans-sialidase family analyzed with camelids single-domain antibodies.Intranasal vaccinations with the trans-sialidase antigen plus CpG Adjuvant induce mucosal immunity protective against conjunctival Trypanosoma cruzi challenges.A synthetic peptide from Trypanosoma cruzi mucin-like associated surface protein as candidate for a vaccine against Chagas diseaseCo-administration of a plasmid DNA encoding IL-15 improves long-term protection of a genetic vaccine against Trypanosoma cruziCD8(+) T cell-mediated immunity during Trypanosoma cruzi infection: a path for vaccine development?Subdominant/cryptic CD8 T cell epitopes contribute to resistance against experimental infection with a human protozoan parasite.CD8+-T-cell-dependent control of Trypanosoma cruzi infection in a highly susceptible mouse strain after immunization with recombinant proteins based on amastigote surface protein 2.Recombinant yellow fever viruses elicit CD8+ T cell responses and protective immunity against Trypanosoma cruziTcVac3 induced control of Trypanosoma cruzi infection and chronic myocarditis in mice.Biological and immunological characterization of recombinant Yellow Fever 17D viruses expressing a Trypanosoma cruzi Amastigote Surface Protein-2 CD8+ T cell epitope at two distinct regions of the genomeHeterologous plasmid DNA prime-recombinant human adenovirus 5 boost vaccination generates a stable pool of protective long-lived CD8(+) T effector memory cells specific for a human parasite, Trypanosoma cruziAnatomical route of invasion and protective mucosal immunity in Trypanosoma cruzi conjunctival infection.Antigen targeting to dendritic cells allows the identification of a CD4 T-cell epitope within an immunodominant Trypanosoma cruzi antigenThe Immune Response to Trypanosoma cruzi: Role of Toll-Like Receptors and Perspectives for Vaccine Development.Parasite-induced chronic inflammation is not exacerbated by immunotherapy before or during Trypanosoma cruzi Infection.Induction of cardiac autoimmunity in Chagas heart disease: a case for molecular mimicry.Novel protective antigens expressed by Trypanosoma cruzi amastigotes provide immunity to mice highly susceptible to Chagas' disease.DNA Vaccines against Protozoan Parasites: Advances and ChallengesChagas' disease: an update on immune mechanisms and therapeutic strategiesPerforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.The endless race between Trypanosoma cruzi and host immunity: lessons for and beyond Chagas disease.LFA-1 Mediates Cytotoxicity and Tissue Migration of Specific CD8+ T Cells after Heterologous Prime-Boost Vaccination against Trypanosoma cruzi Infection.Distinct kinetics of effector CD8+ cytotoxic T cells after infection with Trypanosoma cruzi in naive or vaccinated mice.Protective immunity against Trypanosoma cruzi.Evaluation of immune responses raised against Tc13 antigens of Trypanosoma cruzi in the outcome of murine experimental infection.Immune system pathogenesis is prevented by the neutralization of the systemic trans-sialidase from Trypanosoma cruzi during severe infections
P2860
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P2860
Protective Immunity Against Trypanosoma cruzi Infection in a Highly Susceptible Mouse Strain After Vaccination with Genes Encoding the Amastigote Surface Protein-2 and Trans-Sialidase
description
article
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2004
@uk
name
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@en
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@nl
type
label
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@en
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@nl
prefLabel
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@en
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@nl
P2093
P50
P921
P356
P1433
P1476
Protective Immunity Against Tr ...... Protein-2 and Trans-Sialidase
@en
P2093
Cláudio R.F. Marinho
José M. Alvarez
José Ronnie Vasconcelos
Mauricio M. Rodrigues
Meire I. Hiyane
Oscar Bruña-Romero
Ricardo T. Gazzinelli
P304
P356
10.1089/HUM.2004.15.878
P577
2004-09-01T00:00:00Z