Dual mechanism of microenvironmental pH modulation and foam melt extrusion to enhance performance of HPMCAS based amorphous solid dispersion

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Dual mechanism of microenvironmental pH modulation and foam melt extrusion to enhance performance of HPMCAS based amorphous solid dispersion

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im Oktober 2018 veröffentlichter wissenschaftlicher Artikel

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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name

Dual mechanism of microenviron ...... sed amorphous solid dispersion

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Dual mechanism of microenviron ...... sed amorphous solid dispersion

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Dual mechanism of microenviron ...... sed amorphous solid dispersion

@en

Dual mechanism of microenviron ...... sed amorphous solid dispersion

@nl

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Dual mechanism of microenviron ...... sed amorphous solid dispersion

@en

Dual mechanism of microenviron ...... sed amorphous solid dispersion

@nl

P1476

Dual mechanism of microenviron ...... sed amorphous solid dispersion

@en

P2093

Anh Q Vo

http://www.w3.org/2001/XMLSchema#string

Feng Zhang

http://www.w3.org/2001/XMLSchema#string

Jiaxiang Zhang

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Michael A Repka

http://www.w3.org/2001/XMLSchema#string

Xin Feng

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P2860

Mechanistic differences in permeation behavior of supersaturated and solubilized solutions of carbamazepine revealed by nuclear magnetic resonance measurements.

Supersaturating drug delivery systems: the answer to solubility-limited oral bioavailability?

A novel floating controlled release drug delivery system prepared by hot-melt extrusion.

Microenvironmental pH modulation in solid dosage forms.

Solid dispersions as strategy to improve oral bioavailability of poor water soluble drugs.

Using polymeric precipitation inhibitors to improve the absorption of poorly water-soluble drugs: A mechanistic basis for utility.

Application of mid-IR spectroscopy for the characterization of pharmaceutical systems.

Strategies to address low drug solubility in discovery and development.

Microenvironmental pH-modification to improve dissolution behavior and oral absorption for drugs with pH-dependent solubility.

Refining stability and dissolution rate of amorphous drug formulations.

P304

216-228

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P31

scholarly article

P356

10.1016/J.IJPHARM.2018.08.042

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P407

English

P433

1-2

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P478

550

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P577

2018-10-25T00:00:00Z

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P698

30142354

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P932

6158015

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