Motor-free mitochondrial presequence translocase drives membrane integration of preproteins
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Structural Basis for the Function of Tim50 in the Mitochondrial Presequence TranslocaseThe translocator maintenance protein Tam41 is required for mitochondrial cardiolipin biosynthesis.Phosphatidylethanolamine biosynthesis in mitochondria: phosphatidylserine (PS) trafficking is independent of a PS decarboxylase and intermembrane space proteins UPS1P and UPS2P.Ups1p and Ups2p antagonistically regulate cardiolipin metabolism in mitochondria.The mitochondrial oxidase assembly protein1 (Oxa1) insertase forms a membrane pore in lipid bilayers.Deacylation on the matrix side of the mitochondrial inner membrane regulates cardiolipin remodeling.Signal recognition initiates reorganization of the presequence translocase during protein import.The mitochondrial ADP/ATP carrier associates with the inner membrane presequence translocase in a stoichiometric manner.Role for two conserved intermembrane space proteins, Ups1p and Ups2p, [corrected] in intra-mitochondrial phospholipid trafficking.Mitochondrial protein import motor: differential role of Tim44 in the recruitment of Pam17 and J-complex to the presequence translocase.Mgr2 promotes coupling of the mitochondrial presequence translocase to partner complexes.FMP30 is required for the maintenance of a normal cardiolipin level and mitochondrial morphology in the absence of mitochondrial phosphatidylethanolamine synthesis.Stepwise assembly of dimeric F(1)F(o)-ATP synthase in mitochondria involves the small F(o)-subunits k and i.Disorders of phospholipid metabolism: an emerging class of mitochondrial disease due to defects in nuclear genesCellular functions of cardiolipin in yeastImporting mitochondrial proteins: machineries and mechanismsGranzyme B enters the mitochondria in a Sam50-, Tim22- and mtHsp70-dependent manner to induce apoptosis.Role of phosphatidylethanolamine in the biogenesis of mitochondrial outer membrane proteinsCardiolipin, a critical determinant of mitochondrial carrier protein assembly and function.The minimal proteome in the reduced mitochondrion of the parasitic protist Giardia intestinalis.Mitochondrial protein synthesis, import, and assembly.The cell-free integration of a polytopic mitochondrial membrane protein into liposomes occurs cotranslationally and in a lipid-dependent manner.Mitochondrial protein import and the genesis of steroidogenic mitochondriaTim50's presequence receptor domain is essential for signal driven transport across the TIM23 complexThe fusogenic lipid phosphatidic acid promotes the biogenesis of mitochondrial outer membrane protein Ugo1Lipid-mediated unfolding of 3β-hydroxysteroid dehydrogenase 2 is essential for steroidogenic activity.Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40.The power of yeast to model diseases of the powerhouse of the cell.Unremodeled and remodeled cardiolipin are functionally indistinguishable in yeast.Two distinct membrane potential-dependent steps drive mitochondrial matrix protein translocation.Electrophysiology clarifies the megariddles of the mitochondrial permeability transition pore.Mechanisms of protein sorting in mitochondriaMitochondrial protein homeostasis.Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond.Role of membrane contact sites in protein import into mitochondria.Mechanisms Regulating Protein Localization.Angiotensinogen import in isolated proximal tubules: evidence for mitochondrial trafficking and uptake.Revisiting trends on mitochondrial mega-channels for the import of proteins and nucleic acids.Targeting mitochondria: how intravacuolar bacterial pathogens manipulate mitochondria.Mitochondrial protein import in trypanosomes: Expect the unexpected.
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Motor-free mitochondrial presequence translocase drives membrane integration of preproteins
description
im September 2007 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2007
@uk
name
Motor-free mitochondrial prese ...... ane integration of preproteins
@en
Motor-free mitochondrial prese ...... ane integration of preproteins
@nl
type
label
Motor-free mitochondrial prese ...... ane integration of preproteins
@en
Motor-free mitochondrial prese ...... ane integration of preproteins
@nl
prefLabel
Motor-free mitochondrial prese ...... ane integration of preproteins
@en
Motor-free mitochondrial prese ...... ane integration of preproteins
@nl
P2093
P2860
P356
P1433
P1476
Motor-free mitochondrial prese ...... ane integration of preproteins
@en
P2093
Bernard Guiard
Dana P. Hutu
Inge Perschil
Maria Lind
Nikolaus Pfanner
Peter Rehling
Richard Wagner
P2860
P2888
P304
P356
10.1038/NCB1635
P577
2007-09-09T00:00:00Z