Interferon-α prevents apoptosis of endothelial cells after short-term exposure but induces replicative senescence after continuous stimulation
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Pathophysiological role of guanylate-binding proteins in gastrointestinal diseasesHuman guanylate binding proteins potentiate the anti-chlamydia effects of interferon-gamma.IFNα-mediated remodeling of endothelial cells in the bone marrow niche.Guanylate-binding protein-1 is expressed at tight junctions of intestinal epithelial cells in response to interferon-gamma and regulates barrier function through effects on apoptosis.Interferon-β induces cellular senescence in cutaneous human papilloma virus-transformed human keratinocytes by affecting p53 transactivating activitySU5416 induces premature senescence in endothelial progenitor cells from patients with age-related macular degeneration.Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct.The PI3K/Akt/mTOR pathway is implicated in the premature senescence of primary human endothelial cells exposed to chronic radiationCommensal Escherichia coli reduces epithelial apoptosis through IFN-alphaA-mediated induction of guanylate binding protein-1 in human and murine models of developing intestine.Guanine nucleotide-binding protein 1 is one of the key molecules contributing to cancer cell radioresistanceRole of Calprotectin as a Modulator of the IL27-Mediated Proinflammatory Effect on Endothelial Cells.IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells.Premature vascular damage in systemic lupus erythematosus.The guanylate-binding proteins: emerging insights into the biochemical properties and functions of this family of large interferon-induced guanosine triphosphataseThe role of cytokines in skin aging.Cardiac Fibroblast Transcriptome Analyses Support a Role for Interferogenic, Profibrotic and Inflammatory Genes in Anti-SSA/Ro-Associated Congenital Heart Block.The Protective Role of Type I Interferons in the Gastrointestinal Tract.GBP-1 acts as a tumor suppressor in colorectal cancer cells.Endothelial progenitor dysfunction associates with a type I interferon signature in primary antiphospholipid syndrome.A potential contribution of antimicrobial peptide LL-37 to tissue fibrosis and vasculopathy in systemic sclerosis.Leptin and Neutrophil-Activating Peptide 2 Promote Mesenchymal Stem Cell Senescence Through Activation of the Phosphatidylinositol 3-Kinase/Akt Pathway in Patients With Systemic Lupus Erythematosus.Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity.
P2860
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P2860
Interferon-α prevents apoptosis of endothelial cells after short-term exposure but induces replicative senescence after continuous stimulation
description
im August 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в серпні 2006
@uk
name
Interferon-α prevents apoptosi ...... e after continuous stimulation
@en
Interferon-α prevents apoptosi ...... e after continuous stimulation
@nl
type
label
Interferon-α prevents apoptosi ...... e after continuous stimulation
@en
Interferon-α prevents apoptosi ...... e after continuous stimulation
@nl
prefLabel
Interferon-α prevents apoptosi ...... e after continuous stimulation
@en
Interferon-α prevents apoptosi ...... e after continuous stimulation
@nl
P2093
P2860
P1476
Interferon-α prevents apoptosi ...... e after continuous stimulation
@en
P2093
Christine Reinisch
Johannes Pammer
Kristin Pogoda
Peter Birner
P2860
P2888
P304
P356
10.1038/LABINVEST.3700461
P577
2006-08-07T00:00:00Z