Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25 - Wikidata - awgldk - TriplyDB

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

http://www.wikidata.org/entity/Q57979097

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SV2 mediates entry of tetanus neurotoxin into central neurons Expression of genes encoding multi-transmembrane proteins in specific primate taste cell populations Discovery of a novel enzymatic cleavage site for botulinum neurotoxin F5 Identification of a novel syntaxin- and synaptobrevin/VAMP-binding protein, SNAP-23, expressed in non-neuronal tissues Endobrevin, a novel synaptobrevin/VAMP-like protein preferentially associated with the early endosome The cysteine-string domain of the secretory vesicle cysteine-string protein is required for membrane targeting SNAP-25a and -25b isoforms are both expressed in insulin-secreting cells and can function in insulin secretion Release, neuronal effects and removal of extracellular β-nicotinamide adenine dinucleotide (β-NAD⁺) in the rat brain Membrane fusion: grappling with SNARE and SM proteins A novel tetanus neurotoxin-insensitive vesicle-associated membrane protein in SNARE complexes of the apical plasma membrane of epithelial cells rbSec1A and B colocalize with syntaxin 1 and SNAP-25 throughout the axon, but are not in a stable complex with syntaxin LTP requires a unique postsynaptic SNARE fusion machinery Synaptic vesicle exocytosis Membrane fusion as a team effort alpha-latrotoxin triggers transmitter release via direct insertion into the presynaptic plasma membrane Spotlight on botulinum toxin and its potential in the treatment of stroke-related spasticity Current status and future directions of botulinum neurotoxins for targeting pain processing Mass Spectrometric Detection of Bacterial Protein Toxins and Their Enzymatic Activity Distinct initial SNARE configurations underlying the diversity of exocytosis miR-153 regulates SNAP-25, synaptic transmission, and neuronal development High resolution structure, stability, and synaptotagmin binding of a truncated neuronal SNARE complex A Potent Peptidomimetic Inhibitor of Botulinum Neurotoxin Serotype A Has a Very Different Conformation than SNAP-25 Substrate Iterative Structure-Based Peptide-Like Inhibitor Design against the Botulinum Neurotoxin Serotype A Unique Ganglioside Recognition Strategies for Clostridial Neurotoxins High-resolution crystal structure of HA33 of botulinum neurotoxin type B progenitor toxin complex Vam7p, a vacuolar SNAP-25 homolog, is required for SNARE complex integrity and vacuole docking and fusion.Analysis of a yeast SNARE complex reveals remarkable similarity to the neuronal SNARE complex and a novel function for the C terminus of the SNAP-25 homolog, Sec9.Tlg2p, a yeast syntaxin homolog that resides on the Golgi and endocytic structures.Botulinum Toxin A for Controlling Obesity History of Botulinum Toxin Treatment in Movement Disorders Botulinum Toxin as a Pain Killer: Players and Actions in Antinociception The N-ethylmaleimide-sensitive fusion protein and alpha-SNAP induce a conformational change in syntaxin Botulinum neurotoxin serotype A specific cell-based potency assay to replace the mouse bioassay Phosphatase Inhibitors Function as Novel, Broad Spectrum Botulinum Neurotoxin Antagonists in Mouse and Human Embryonic Stem Cell-Derived Motor Neuron-Based Assays A second SNARE role for exocytic SNAP25 in endosome fusion Cellubrevin and synaptobrevins: similar subcellular localization and biochemical properties in PC12 cells Mechanism of action of tetanus and botulinum neurotoxins Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds Proteolysis of SNAP-25 isoforms by botulinum neurotoxin types A, C, and E: domains and amino acid residues controlling the formation of enzyme-substrate complexes and cleavage Atoxic derivative of botulinum neurotoxin A as a prototype molecular vehicle for targeted delivery to the neuronal cytoplasm

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Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

http://www.wikidata.org/entity/Q57979097

description

article publié dans la revue scientifique Nature

@fr

scientific article published in Nature

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature у вересні 1993

@uk

name

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@en

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@nl

type

label

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@en

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@nl

prefLabel

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@en

Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

@nl

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Botulinum neurotoxin A selectively cleaves the synaptic protein SNAP-25

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Edwin R. Chapman

http://www.w3.org/2001/XMLSchema#string

Egenhard Link

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Heiner Niemann

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Juan Blasi

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Shinji Yamasaki

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Thomas Binz

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160-163

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scholarly article

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10.1038/365160A0

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Pietro De Camilli

Thomas C. Südhof

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1993-09-01T00:00:00Z

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1009090482

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8103915

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