QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes

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QM/MM simulations identify the determinants of catalytic activity differences between type II dehydroquinase enzymes

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im Juni 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 01 June 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в червні 2018

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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QM/MM simulations identify the ...... type II dehydroquinase enzymes

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P1476

QM/MM simulations identify the ...... type II dehydroquinase enzymes

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P2093

Adrian J Mulholland

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H++: a server for estimating pKas and adding missing hydrogens to macromolecules

The structure and mechanism of the type II dehydroquinase from Streptomyces coelicolor

Specificity of substrate recognition by type II dehydroquinases as revealed by binding of polyanions

Synthesis and biological evaluation of new nanomolar competitive inhibitors of Helicobacter pylori type II dehydroquinase. Structural details of the role of the aromatic moieties with essential residues

Understanding the key factors that control the inhibition of type II dehydroquinase by (2R)-2-benzyl-3-dehydroquinic acids

Structural investigation of inhibitor designs targeting 3-dehydroquinate dehydratase from the shikimate pathway of Mycobacterium tuberculosis

A prodrug approach for improving antituberculosis activity of potent Mycobacterium tuberculosis type II dehydroquinase inhibitors

The basis for carbapenem hydrolysis by class A β-lactamases: a combined investigation using crystallography and simulations

Mechanistic basis of the inhibition of type II dehydroquinase by (2S)- and (2R)-2-benzyl-3-dehydroquinic acids

The Catalytic Mechanism of a Natural Diels-Alderase Revealed in Molecular Detail

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4443-4455

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scholarly article

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10.1039/C8OB00066B

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English

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P478

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Concepcion Gonzalez-bello

Marc van der Kamp

Emilio Lence

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2018-06-01T00:00:00Z

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P698

29767194

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6011038

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