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Rise and fall of an anti-MUC1 specific antibodyModern Technologies for Creating Synthetic Antibodies for Clinical application.Bioengineering a unique deimmunized bispecific targeted toxin that simultaneously recognizes human CD22 and CD19 receptors in a mouse model of B-cell metastases.Evaluation of human pancreatic RNase as effector molecule in a therapeutic antibody platform.Targeting antibodies to the cytoplasm.CD30 as a therapeutic target for lymphoma.Killing of cancer cells through the use of eukaryotic expression vectors harbouring genes encoding nucleases and ribonuclease inhibitor.Genetic delivery of an immunoRNase by an oncolytic adenovirus enhances anticancer activity.Engineered human angiogenin mutations in the placental ribonuclease inhibitor complex for anticancer therapy: Insights from enhanced sampling simulations.Development of a Deimmunized Bispecific Immunotoxin dDT2219 against B-Cell Malignancies.Updates in the Development of ImmunoRNases for the Selective Killing of Tumor Cells.The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.
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description
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в грудні 2008
@uk
name
Targeted therapeutic RNases (ImmunoRNases)
@en
Targeted therapeutic RNases
@nl
type
label
Targeted therapeutic RNases (ImmunoRNases)
@en
Targeted therapeutic RNases
@nl
prefLabel
Targeted therapeutic RNases (ImmunoRNases)
@en
Targeted therapeutic RNases
@nl
P2093
P2860
P1476
Targeted therapeutic RNases (ImmunoRNases)
@en
P2093
Jürgen Krauss
Michaela AE Arndt
Susanna M Rybak
Thomas Schirrmann
P2860
P356
10.1517/14712590802631862
P407
P50
P577
2008-12-08T00:00:00Z