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Structural and mechanistic insights into the interaction of cytochrome P4503A4 with bromoergocryptine, a type I ligandElectron flow through biological molecules: does hole hopping protect proteins from oxidative damage?Understanding the mechanism of cytochrome P450 3A4: recent advances and remaining problemsA novel type of allosteric regulation: functional cooperativity in monomeric proteinsDeterminants of Cytochrome P450 2C8 Substrate Binding: STRUCTURES OF COMPLEXES WITH MONTELUKAST, TROGLITAZONE, FELODIPINE, AND 9-CIS-RETINOIC ACIDUse of chemical auxiliaries to control p450 enzymes for predictable oxidations at unactivated C-h bonds of substratesRedox potential control by drug binding to cytochrome P450 3A4Fast Photochemical Oxidation of Proteins Maps the Topology of Intrinsic Membrane Proteins: Light-Harvesting Complex 2 in a Nanodisc.Nanomechanical detection of cholera toxin using microcantilevers functionalized with ganglioside nanodiscs.Peripheral ligand-binding site in cytochrome P450 3A4 located with fluorescence resonance energy transfer (FRET)Using resonance Raman cross-section data to estimate the spin state populations of Cytochromes P450.Modulation of the cytochrome P450 reductase redox potential by the phospholipid bilayer.Nanodisc-incorporated hemagglutinin provides protective immunity against influenza virus infection.Calcium-dependent ligand binding and G-protein signaling of family B GPCR parathyroid hormone 1 receptor purified in nanodiscs.Conformational equilibria of light-activated rhodopsin in nanodiscs.Ultra-thin layer MALDI mass spectrometry of membrane proteins in nanodiscs.Lipid-protein correlations in nanoscale phospholipid bilayers determined by solid-state nuclear magnetic resonance.Cytochromes P450 in nanodiscs.A series of hybrid P450 BM3 enzymes with different catalytic activity in the light-initiated hydroxylation of lauric acidDefining CYP3A4 structural responses to substrate binding. Raman spectroscopic studies of a nanodisc-incorporated mammalian cytochrome P450.Analysis of heterotropic cooperativity in cytochrome P450 3A4 using alpha-naphthoflavone and testosterone.Nanodisc-solubilized membrane protein library reflects the membrane proteome.Interactions of cytochrome P450s with their ligands.Magic-angle spinning solid-state NMR spectroscopy of nanodisc-embedded human CYP3A4.Screening of type I and II drug binding to human cytochrome P450-3A4 in nanodiscs by localized surface plasmon resonance spectroscopy.Membrane protein assembly into Nanodiscs.Could tyrosine and tryptophan serve multiple roles in biological redox processes?Solid-state NMR of the Yersinia pestis outer membrane protein Ail in lipid bilayer nanodiscs sedimented by ultracentrifugation.Green proteorhodopsin reconstituted into nanoscale phospholipid bilayers (nanodiscs) as photoactive monomers.Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand InteractionsStructural and Functional Analysis of Calcium Ion Mediated Binding of 5-Lipoxygenase to NanodiscsHAMP domain signal relay mechanism in a sensory rhodopsin-transducer complexEnergetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4Mechanism of drug-drug interactions mediated by human cytochrome P450 CYP3A4 monomerBiophysical characterization of membrane proteins in nanodiscs.The ferrous-oxy complex of human aromatasePolyprotein context regulates the activity of poliovirus 2CATPase bound to bilayer nanodiscs.Coumarin Derivatives as Substrate Probes of Mammalian Cytochromes P450 2B4 and 2B6: Assessing the Importance of 7-Alkoxy Chain Length, Halogen Substitution, and Non-Active Site Mutations.Atomic-level description of protein-lipid interactions using an accelerated membrane model.Characterizing the membrane-bound state of cytochrome P450 3A4: structure, depth of insertion, and orientation.
P2860
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P2860
description
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
im Januar 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published in Journal of Biological Chemistry
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2007
@uk
name
Cooperativity in Cytochrome P450 3A4
@en
Cooperativity in Cytochrome P450 3A4
@nl
type
label
Cooperativity in Cytochrome P450 3A4
@en
Cooperativity in Cytochrome P450 3A4
@nl
prefLabel
Cooperativity in Cytochrome P450 3A4
@en
Cooperativity in Cytochrome P450 3A4
@nl
P2093
P2860
P356
P1476
Cooperativity in cytochrome P4 ...... oupling, and product formation
@en
P2093
Bradley J Baas
Stephen G Sligar
Yelena V Grinkova
P2860
P304
P356
10.1074/JBC.M609589200
P407
P577
2007-01-09T00:00:00Z