High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

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http://www.wikidata.org/entity/Q58041746
The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA.Melanoma differentiation associated gene-7/interleukin-24 potently induces apoptosis in human myeloid leukemia cells through a process regulated by endoplasmic reticulum stress.A novel piperazine derivative potently induces caspase-dependent apoptosis of cancer cells via inhibition of multiple cancer signaling pathwaysCD47-retargeted oncolytic adenovirus armed with melanoma differentiation-associated gene-7/interleukin-24 suppresses in vivo leukemia cell growthMelanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.IL-24: a classic cytokine and/or a potential cure for cancer?Pro-survival signal inhibition by CDK inhibitor dinaciclib in Chronic Lymphocytic Leukaemia.Inhibition of autophagy induced by overexpression of mda-7/interleukin-24 strongly augments the antileukemia activity in vitro and in vivo.Cellular origin and pathophysiology of chronic lymphocytic leukemia.The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease.Ability to downregulate the level of cyclin-dependent kinase inhibitor p27Kip1 after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway.Interleukin-24 mediates apoptosis in human B-cells through early activation of cell cycle arrest followed by late induction of the mitochondrial apoptosis pathway.Lyn-mediated SHP-1 recruitment to CD5 contributes to resistance to apoptosis of B-cell chronic lymphocytic leukemia cells.
P2860

High Mda-7 expression promotes malignant cell survival and p38 MAP kinase activation in chronic lymphocytic leukemia

Item
http://www.wikidata.org/entity/Q58041746
description
im Januar 2006 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в січні 2006
@uk
name
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@en
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@nl
type
label
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@en
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@nl
prefLabel
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@en
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P698
P921
P356
P1433
P1476
High Mda-7 expression promotes ...... n chronic lymphocytic leukemia
@en
P2093
P2860
P2888
P304
P31
P356
P433
P478
P50
P577
P698
P921