Beyond odds ratios — communicating disease risk based on genetic profiles
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Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studiesReplication in Genome-Wide Association StudiesThe genetics of cancer riskGenome-wide association studies and beyondCirculating mitochondrial DNA in patients in the ICU as a marker of mortality: derivation and validationRecent advances of genetic ancestry testing in biomedical research and direct to consumer testingRegularized Machine Learning in the Genetic Prediction of Complex TraitsPrediction and interaction in complex disease genetics: experience in type 1 diabetes.The genetic interpretation of area under the ROC curve in genomic profilingWhat role for genetics in the prediction of multiple sclerosis?Genetic variants and their interactions in the prediction of increased pre-clinical carotid atherosclerosis: the cardiovascular risk in young Finns study.The PXR rs7643645 polymorphism is associated with the risk of higher prostate-specific antigen levels in prostate cancer patientsA unifying framework for evaluating the predictive power of genetic variants based on the level of heritability explained.Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women.Leveraging human genetics to develop future therapeutic strategies in rheumatoid arthritisCoding variants in nephrin (NPHS1) and susceptibility to nephropathy in African Americans.Performance of common genetic variants in breast-cancer risk models.The emergence of translational epidemiology: from scientific discovery to population health impact.Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.The Scientific Foundation for personal genomics: recommendations from a National Institutes of Health-Centers for Disease Control and Prevention multidisciplinary workshop.Multistage analysis strategies for genome-wide association studies: summary of group 3 contributions to Genetic Analysis Workshop 16.Bayesian analysis of genetic interactions in case-control studies, with application to adiponectin genes and colorectal cancer risk.Caution in generalizing known genetic risk markers for breast cancer across all ethnic/racial populationsIntegrating genetics and social science: genetic risk scoresGenetics of cerebral small vessel diseaseA stratified genetic risk assessment for testicular cancerPhenotype-optimized sequence ensembles substantially improve prediction of disease-causing mutation in cystic fibrosis.The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) StudyPredictive genetic testing for the identification of high-risk groups: a simulation study on the impact of predictive ability.New variants at 10q26 and 15q21 are associated with aggressive prostate cancer in a genome-wide association study from a prostate biopsy screening cohort.Discriminatory accuracy and potential clinical utility of genomic profiling for breast cancer risk in BRCA-negative womenMachine learning derived risk prediction of anorexia nervosaSummarizing polygenic risks for complex diseases in a clinical whole-genome reportEstimation of effect size distribution from genome-wide association studies and implications for future discoveries.Polygenic Scores in Epidemiology: Risk Prediction, Etiology, and Clinical UtilityStrategies to predict rheumatoid arthritis development in at-risk populations.Genome-wide association studies in preterm birth: implications for the practicing obstetrician-gynaecologist."Is it really worth it to get tested?": primary care patients' impressions of predictive SNP testing for colon cancer.Genetic variants and their interactions in disease risk prediction - machine learning and network perspectivesRegulatory polymorphisms modulate the expression of HLA class II molecules and promote autoimmunity.
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Beyond odds ratios — communicating disease risk based on genetic profiles
description
article
@en
im April 2009 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована у квітні 2009
@uk
name
Beyond odds ratios — communicating disease risk based on genetic profiles
@en
Beyond odds ratios — communicating disease risk based on genetic profiles
@nl
type
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Beyond odds ratios — communicating disease risk based on genetic profiles
@en
Beyond odds ratios — communicating disease risk based on genetic profiles
@nl
prefLabel
Beyond odds ratios — communicating disease risk based on genetic profiles
@en
Beyond odds ratios — communicating disease risk based on genetic profiles
@nl
P2093
P50
P356
P1476
Beyond odds ratios — communicating disease risk based on genetic profiles
@en
P2093
Frank B. Hu
Gilles Thomas
Marilyn C. Cornelis
Peter Kraft
Richard B. Hayes
Robert Hoover
P2860
P2888
P304
P356
10.1038/NRG2516
P577
2009-04-01T00:00:00Z
P6179
1027055889