about
Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligandsThe Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.Lack of glucocorticoid-induced leucine zipper (GILZ) deregulates B-cell survival and results in B-cell lymphocytosis in mice.BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosisGpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases.Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice.Recombinant long-glucocorticoid-induced leucine zipper (L-GILZ) protein restores the control of proliferation in gilz KO spermatogonia.Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.Bile Acids Activated Receptors Regulate Innate ImmunityFuture trends in the treatment of non-alcoholic steatohepatitisAgonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitisGlucocorticoid-Induced Leucine Zipper (GILZ) Controls Inflammation and Tissue Damage after Spinal Cord InjuryGILZ Promotes Production of Peripherally Induced Treg Cells and Mediates the Crosstalk between Glucocorticoids and TGF-β SignalingDivergent Effectiveness of Multispecies Probiotic Preparations on Intestinal Microbiota Structure Depends on Metabolic PropertiesTranscriptome Analysis of Dual FXR and GPBAR1 Agonism in Rodent Model of NASH Reveals Modulation of Lipid Droplets Formation.Immunephenotype Predicts Response to Vedolizumab: Integrating Clinical and Biochemical Biomarkers in the Treatment of Inflammatory Bowel DiseasesThe Bile Acid Receptor GPBAR1 Modulates CCL2/CCR2 Signaling at the Liver Sinusoidal/Macrophage Interface and Reverses Acetaminophen-Induced Liver ToxicityUrsodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASHSignaling from Intestine to the Host: How Bile Acids Regulate Intestinal and Liver ImmunityThe Aryl Hydrocarbon Receptor (AhR) Mediates the Counter-Regulatory Effects of Pelargonidins in Models of Inflammation and Metabolic DysfunctionsGPBAR1 Functions as Gatekeeper for Liver NKT Cells and provides Counterregulatory Signals in Mouse Models of Immune-Mediated HepatitisNovel Isoxazole Derivatives with Potent FXR Agonistic Activity Prevent Acetaminophen-Induced Liver Injury
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description
researcher, ORCID id # 0000-0002-2995-6896
@en
wetenschapper
@nl
name
Michele Biagioli
@ast
Michele Biagioli
@en
Michele Biagioli
@es
Michele Biagioli
@nl
type
label
Michele Biagioli
@ast
Michele Biagioli
@en
Michele Biagioli
@es
Michele Biagioli
@nl
prefLabel
Michele Biagioli
@ast
Michele Biagioli
@en
Michele Biagioli
@es
Michele Biagioli
@nl
P106
P1153
56090527800
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P31
P496
0000-0002-2995-6896