Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations
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Models for Predicting Drug Absorption From Oral Lipid-Based FormulationsPharmacokinetic aspects and in vitro-in vivo correlation potential for lipid-based formulationsEffect of ingested lipids on drug dissolution and release with concurrent digestion: a modeling approach.In vitro lipolysis data does not adequately predict the in vivo performance of lipid-based drug delivery systems containing fenofibrate.Toward the establishment of standardized in vitro tests for lipid-based formulations, part 6: effects of varying pancreatin and calcium levelsCharacterising lipid lipolysis and its implication in lipid-based formulation development.Computational prediction of drug solubility in lipid based formulation excipients.Development of the Digestive System-Experimental Challenges and Approaches of Infant Lipid Digestion.Transforming lipid-based oral drug delivery systems into solid dosage forms: an overview of solid carriers, physicochemical properties, and biopharmaceutical performance.Lipid-based formulations and drug supersaturation: harnessing the unique benefits of the lipid digestion/absorption pathway.Nanoemulsion-based oral delivery systems for lipophilic bioactive components: nutraceuticals and pharmaceuticals.Self-assembled structures formed during lipid digestion: characterization and implications for oral lipid-based drug delivery systems.Relevant pH and lipase for in vitro models of gastric digestion.The Precipitation Behavior of Poorly Water-Soluble Drugs with an Emphasis on the Digestion of Lipid Based Formulations.Infant digestion physiology and the relevance of in vitro biochemical models to test infant formula lipid digestion.Lipid-associated oral delivery: Mechanisms and analysis of oral absorption enhancement.Toward the establishment of standardized in vitro tests for lipid-based formulations. 5. Lipolysis of representative formulations by gastric lipase.Comparison of lipases for in vitro models of gastric digestion: lipolysis using two infant formulas as model substrates.Tools for Early Prediction of Drug Loading in Lipid-Based Formulations.Dietary fats and pharmaceutical lipid excipients increase systemic exposure to orally administered cannabis and cannabis-based medicines.The Biopharmaceutics Classification System: subclasses for in vivo predictive dissolution (IPD) methodology and IVIVCStatistical investigation of simulated fed intestinal media composition on the equilibrium solubility of oral drugsBiopharmaceutical modeling of drug supersaturation during lipid-based formulation digestion considering an absorption sink.Insights into drug precipitation kinetics during in vitro digestion of a lipid-based drug delivery system using in-line raman spectroscopy and mathematical modeling.Development and in vitro characterization of self-emulsifying drug delivery system (SEDDS) for oral opioid peptide delivery.Toward the establishment of standardized in vitro tests for lipid-based formulations, part 3: understanding supersaturation versus precipitation potential during the in vitro digestion of type I, II, IIIA, IIIB and IV lipid-based formulations.Fate of nanostructured lipid carriers (NLCs) following the oral route: design, pharmacokinetics and biodistribution.Enhanced delivery of lipophilic bioactives using emulsions: a review of major factors affecting vitamin, nutraceutical, and lipid bioaccessibility.In vitro digestion of the self-emulsifying lipid excipient Labrasol(®) by gastrointestinal lipases and influence of its colloidal structure on lipolysis rate.Water-in-oil microemulsions versus emulsions as carriers of hydroxytyrosol: an in vitro gastrointestinal lipolysis study using the pHstat technique.Incorporation of lipolysis in monolayer permeability studies of lipid-based oral drug delivery systems.Caco-2 Cell Conditions Enabling Studies of Drug Absorption from Digestible Lipid-Based Formulations.Solid Lipid Particles for Oral Delivery of Peptide and Protein Drugs II – The Digestion of Trilaurin Protects Desmopressin from Proteolytic DegradationIn vitrolipolysis tests on lipid nanoparticles: comparison between lipase/co-lipase and pancreatic extract
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Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations, Part 1: Method Parameterization and Comparison of In Vitro Digestion Profiles Across a Range of Representative Formulations
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im September 2012 veröffentlichter wissenschaftlicher Artikel
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scientific article published on 29 May 2012
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wetenschappelijk artikel
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наукова стаття, опублікована у вересні 2012
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name
Toward the Establishment of St ...... of Representative Formulations
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Toward the Establishment of St ...... of Representative Formulations
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type
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Toward the Establishment of St ...... of Representative Formulations
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Toward the Establishment of St ...... of Representative Formulations
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Toward the Establishment of St ...... of Representative Formulations
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Toward the Establishment of St ...... of Representative Formulations
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P2093
P50
P356
P1476
Toward the establishment of st ...... of representative formulations
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P2093
Anette Partheil
Annabel Igonin
Delphine Marchaud
Eduardo Jule
Hassan Benameur
Hywel D Williams
Jan Vertommen
Jean-Claude Bakala-N'Goma
Karen Kleberg
Marilyn Calderone
P304
P356
10.1002/JPS.23205
P407
P577
2012-05-29T00:00:00Z