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Leaky RyR2 trigger ventricular arrhythmias in Duchenne muscular dystrophyAbsence of triadin, a protein of the calcium release complex, is responsible for cardiac arrhythmia with sudden death in humanRemodeling of ryanodine receptor complex causes "leaky" channels: a molecular mechanism for decreased exercise capacityRyanodine receptor leak mediated by caspase-8 activation leads to left ventricular injury after myocardial ischemia-reperfusionDifferential localization of autolyzed calpains 1 and 2 in slow and fast skeletal muscles in the early phase of atrophyRevealing the large-scale network organization of growth hormone-secreting cells.Cellular in vivo imaging reveals coordinated regulation of pituitary microcirculation and GH cell network function.Calcium release channel RyR2 regulates insulin release and glucose homeostasisFrequency-dependent and proarrhythmogenic effects of FK-506 in rat ventricular cells.Time course of individual Ca2+ sparks in frog skeletal muscle recorded at high time resolution.Short-coupled polymorphic ventricular tachycardia at rest linked to a novel ryanodine receptor (RyR2) mutation: leaky RyR2 channels under non-stress conditions.Hidden face of the anterior pituitary.Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.Effects of chronic administration of clenbuterol on contractile properties and calcium homeostasis in rat extensor digitorum longus muscle.The energy disruptor metformin targets mitochondrial integrity via modification of calcium flux in cancer cells.Effects of diabetes on ryanodine receptor Ca release channel (RyR2) and Ca2+ homeostasis in rat heart.Activation of Sonic hedgehog signaling in ventricular cardiomyocytes exerts cardioprotection against ischemia reperfusion injuries.Beneficial effects of SR33805 in failing myocardium.Two mechanisms for termination of individual Ca2+ sparks in skeletal muscleRegulation of cAMP homeostasis by the efflux protein MRP4 in cardiac myocytes.Atomic force microscopy combined with human pluripotent stem cell derived cardiomyocytes for biomechanical sensing.Increase in Cardiac Ischemia-Reperfusion Injuries in Opa1+/- Mouse Model.Antagonism of Nav channels and α1-adrenergic receptors contributes to vascular smooth muscle effects of ranolazine.Voltage dependence of the pattern and frequency of discrete Ca2+ release events after brief repriming in frog skeletal muscle.Repriming and activation alter the frequency of stereotyped discrete Ca2+ release events in frog skeletal muscle.Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging.Osteocalcin Signaling in Myofibers Is Necessary and Sufficient for Optimum Adaptation to ExerciseMaintenance of normal blood pressure is dependent on IP3R1-mediated regulation of eNOS.Leaky ryanodine receptors contribute to diaphragmatic weakness during mechanical ventilation.Carbon monoxide pollution aggravates ischemic heart failure through oxidative stress pathway.Type 2 ryanodine receptor: a novel therapeutic target in myocardial ischemia/reperfusion.Targeting neonatal ischemic brain injury with a pentapeptide-based irreversible caspase inhibitor.Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits.Disruption of calcium transfer from ER to mitochondria links alterations of mitochondria-associated ER membrane integrity to hepatic insulin resistance.Anti-inflammatory drugs as promising cardiovascular treatments.Forced aggregation and defined factors allow highly uniform-sized embryoid bodies and functional cardiomyocytes from human embryonic and induced pluripotent stem cells.Depressing mitochondria-reticulum interactions protects cardiomyocytes from lethal hypoxia-reoxygenation injury.Rapid onset of specific diaphragm weakness in a healthy murine model of ventilator-induced diaphragmatic dysfunction.Carbon monoxide exposure enhances arrhythmia after cardiac stress: involvement of oxidative stress.Human pluripotent stem cell-derived cardiomyocytes as research and therapeutic tools.
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description
researcher, ORCID id # 0000-0003-0264-1787
@en
wetenschapper
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name
Alain Lacampagne
@ast
Alain Lacampagne
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Alain Lacampagne
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Alain Lacampagne
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type
label
Alain Lacampagne
@ast
Alain Lacampagne
@en
Alain Lacampagne
@es
Alain Lacampagne
@nl
prefLabel
Alain Lacampagne
@ast
Alain Lacampagne
@en
Alain Lacampagne
@es
Alain Lacampagne
@nl
P106
P31
P496
0000-0003-0264-1787