High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy
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Histone lysine-specific methyltransferases and demethylases in carcinogenesis: new targets for cancer therapy and preventionStructural Context of Disease-Associated Mutations and Putative Mechanism of Autoinhibition Revealed by X-Ray Crystallographic Analysis of the EZH2-SET DomainPrognostic value of high EZH2 expression in patients with different types of cancer: a systematic review with meta-analysisIncreased HIF-1alpha expression in tumor cells and lymphocytes of tumor microenvironments predicts unfavorable survival in esophageal squamous cell carcinoma patientsRole of EZH2 polymorphisms in esophageal squamous cell carcinoma risk in Han Chinese population.Association of decreased expression of long non-coding RNA LOC285194 with chemoradiotherapy resistance and poor prognosis in esophageal squamous cell carcinoma.The prognostic role of EZH2 expression in rectal cancer patients treated with neoadjuvant chemoradiotherapyThe telomere/telomerase binding factor PinX1 is a new target to improve the radiotherapy effect of oesophageal squamous cell carcinomas.The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinomaEnhancer of zeste homolog 2 as an independent prognostic marker for cancer: a meta-analysisPrognostic significance of histone methyltransferase enhancer of zeste homolog 2 in patients with cervical squamous cell carcinoma.Enhancer of zeste homolog 2 silencing inhibits tumor growth and lung metastasis in osteosarcoma.Higher heat shock factor 1 expression in tumor stroma predicts poor prognosis in esophageal squamous cell carcinoma patientsIncreased WNT6 expression in tumor cells predicts unfavorable survival in esophageal squamous cell carcinoma patientsMicroRNA-98 and microRNA-214 post-transcriptionally regulate enhancer of zeste homolog 2 and inhibit migration and invasion in human esophageal squamous cell carcinomaRole of E2F-1 and its involving pathway in esophageal squamous cell carcinoma.The relationship between EZH2 expression and microRNA-31 in colorectal cancer and the role in evolution of the serrated pathwayHigh expression of long non-coding RNA AFAP1-AS1 predicts chemoradioresistance and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapyThe JAZF1-SUZ12 fusion protein disrupts PRC2 complexes and impairs chromatin repression during human endometrial stromal tumorogenesisEpigenetic and genetic alterations-based molecular classification of head and neck cancer.Molecular genetics of myelofibrosis and its associated disease phenotypes.Epigenetic silencing and activation of transcription: influence on the radiation sensitivity of glioma cell lines.HOTAIR, a prognostic factor in esophageal squamous cell carcinoma, inhibits WIF-1 expression and activates Wnt pathway.Up-regulation of enhancer of zeste homolog 2 is associated positively with cyclin D1 overexpression and poor clinical outcome in head and neck squamous cell carcinoma.EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin.Overexpression of maelstrom promotes bladder urothelial carcinoma cell aggressiveness by epigenetically downregulating MTSS1 through DNMT3B.IncRNA H19 promotes tongue squamous cell carcinoma progression through β-catenin/GSK3β/EMT signaling via association with EZH2.Neutrophil-to-lymphocyte ratio as a prognostic biomarker for patients with locally advanced esophageal squamous cell carcinoma treated with definitive chemoradiotherapy.Targeted disruption of the EZH2-EED complex inhibits EZH2-dependent cancer.Elevated HBXIP expression is associated with aggressive phenotype and poor prognosis in esophageal squamous cell carcinoma.Correlations of EZH2 and SMDY3 Gene Polymorphisms with Breast Cancer Susceptibility and Prognosis.Down-regulation of long non-coding RNA ESCCAL_1 inhibits tumor growth of esophageal squamous cell carcinoma in a xenograft mouse model.The polycomb group protein enhancer of zeste 2 is a novel therapeutic target for cervical cancer.EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients.
P2860
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P2860
High expression of EZH2 is associated with tumor aggressiveness and poor prognosis in patients with esophageal squamous cell carcinoma treated with definitive chemoradiotherapy
description
im November 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 July 2010
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2009
@uk
name
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@en
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@nl
type
label
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@en
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@nl
prefLabel
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@en
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@nl
P2093
P2860
P50
P356
P1476
High expression of EZH2 is ass ...... h definitive chemoradiotherapy
@en
P2093
Bin-Kui Li
Hsiang-Fu Kung
Lan-Jun Zhang
Meng-Zhong Liu
Wei-Hua Jia
Yi-Ji Liao
Yi-Xin Zeng
Ying Zhang
P2860
P304
P356
10.1002/IJC.25031
P577
2010-07-01T00:00:00Z