JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms
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Jun dimerization protein 2 (JDP2), a member of the AP-1 family of transcription factor, mediates osteoclast differentiation induced by RANKLToxicological effects of the different substances in tobacco smoke on human embryonic development by a systems chemo-biology approachMice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defectsThe LIM protein, Limd1, regulates AP-1 activation through an interaction with Traf6 to influence osteoclast developmentMethylsulfonylmethane Inhibits RANKL-Induced Osteoclastogenesis in BMMs by Suppressing NF-κB and STAT3 ActivitiesJun kinase delays caspase-9 activation by interaction with the apoptosomeMolecules and signaling pathways involved in the expression of OC-STAMP during osteoclastogenesisJNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination.Macrophage migration inhibitory factor down-regulates the RANKL-RANK signaling pathway by activating Lyn tyrosine kinase in mouse modelsStrontium-loaded titania nanotube arrays repress osteoclast differentiation through multiple signalling pathways: In vitro and in vivo studiesInteractomics profiling of the negative regulatory function of carbon monoxide on RANKL-treated RAW 264.7 cells during osteoclastogenesisThe large zinc finger protein ZAS3 is a critical modulator of osteoclastogenesis.Peptide YY regulates bone remodeling in mice: a link between gut and skeletal biologyMIP-1δ activates NFATc1 and enhances osteoclastogenesis: involvement of both PLCγ2 and NFκB signaling.Differential regulation of c-Jun-dependent transcription by SUMO-specific proteases.Lactobacillus fermentation enhances the inhibitory effect of Hwangryun-haedok-tang in an ovariectomy-induced bone loss.The polyphenol fisetin protects bone by repressing NF-κB and MKP-1-dependent signaling pathways in osteoclastsAngelica sinensis extract inhibits RANKL-mediated osteoclastogenesis by down-regulated the expression of NFATc1 in mouse bone marrow cellsFra-2/AP-1 controls bone formation by regulating osteoblast differentiation and collagen production.Inactivation of JNK1 enhances innate IL-10 production and dampens autoimmune inflammation in the brain.Inhibitory effect of (-)-epigallocatechin gallate on titanium particle-induced TNF-α release and in vivo osteolysis.Systemic transplantation of human adipose-derived stem cells stimulates bone repair by promoting osteoblast and osteoclast function.Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritisLycorine suppresses RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced osteoporosis and titanium particle-induced osteolysis in vivo.Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling.Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-terminal kinase pathwayThe AP-1 transcription factor homolog Pf-AP-1 activates transcription of multiple biomineral proteins and potentially participates in Pinctada fucata biomineralization.Effects and interaction of icariin, curculigoside, and berberine in er-xian decoction, a traditional chinese medicinal formula, on osteoclastic bone resorption.Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesisThe Src family kinase, Lyn, suppresses osteoclastogenesis in vitro and in vivoTrolox prevents osteoclastogenesis by suppressing RANKL expression and signaling.Osteoclastogenesis and arthritis.Why TNF-α inhibition is not sufficient to avoid juxta-articular erosions in chronic arthritis?12-O-tetradecanoylphorbol-13-acetate (TPA) inhibits osteoclastogenesis by suppressing RANKL-induced NF-kappaB activation.Non-Canonical (RANKL-Independent) Pathways of Osteoclast Differentiation and Their Role in Musculoskeletal Diseases.c-Jun N-Terminal Kinases (JNKs) Are Critical Mediators of Osteoblast Activity In Vivo.Piperine alleviates osteoclast formation through the p38/c-Fos/NFATc1 signaling axis.Monosodium Urate in the Presence of RANKL Promotes Osteoclast Formation through Activation of c-Jun N-Terminal Kinase.Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling.Nordihydroguaiaretic acid inhibition of NFATc1 suppresses osteoclastogenesis and arthritis bone destruction in rats.
P2860
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P2860
JNK1 modulates osteoclastogenesis through both c-Jun phosphorylation-dependent and -independent mechanisms
description
im November 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific article published on 01 November 2002
@en
wetenschappelijk artikel
@nl
наукова стаття, опублікована в листопаді 2002
@uk
name
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@en
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@nl
type
label
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@en
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@nl
prefLabel
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@en
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@nl
P2093
P356
P1476
JNK1 modulates osteoclastogene ...... nt and -independent mechanisms
@en
P2093
Jean-Pierre David
Kanaga Sabapathy
Maria H Idarraga
Oskar Hoffmann
P304
P356
10.1242/JCS.00082
P407
P577
2002-11-01T00:00:00Z