GIP-(3–42) does not antagonize insulinotropic effects of GIP at physiological concentrations
about
Species-specific action of (Pro3)GIP - a full agonist at human GIP receptors, but a partial agonist and competitive antagonist at rat and mouse GIP receptorsN-terminally and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptorAntagonistic effects of two novel GIP analogs, (Hyp3)GIP and (Hyp3)GIPLys16PAL, on the biological actions of GIP and longer-term effects in diabetic ob/ob mice.DPP-4 inhibition increases GIP and decreases GLP-1 incretin effects during intravenous glucose tolerance test in Wistar rats.Effect of vildagliptin, a dipeptidyl peptidase 4 inhibitor, on cardiac hypertrophy induced by chronic beta-adrenergic stimulation in ratsDietary steamed wheat bran increases postprandial fat oxidation in association with a reduced blood glucose-dependent insulinotropic polypeptide response in miceGIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study.
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GIP-(3–42) does not antagonize insulinotropic effects of GIP at physiological concentrations
description
scientific article published on 11 April 2006
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wetenschappelijk artikel
@nl
наукова стаття, опублікована у вересні 2006
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name
GIP-
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GIP-(3–42) does not antagonize ...... t physiological concentrations
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type
label
GIP-
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GIP-(3–42) does not antagonize ...... t physiological concentrations
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prefLabel
GIP-
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GIP-(3–42) does not antagonize ...... t physiological concentrations
@en
P2860
P50
P1476
GIP-(3-42) does not antagonize ...... t physiological concentrations
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P2093
Astrid Plamboeck
Jocelyn de Heer
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P304
P356
10.1152/AJPENDO.00577.2005
P577
2006-04-11T00:00:00Z