Autoamplification and Competition Drive Symmetry Breaking: Initiation of Centriole Duplication by the PLK4-STIL Network

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Autoamplification and Competition Drive Symmetry Breaking: Initiation of Centriole Duplication by the PLK4-STIL Network

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wetenschappelijk artikel

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наукова стаття, опублікована в жовтні 2018

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Autoamplification and Competit ...... ation by the PLK4-STIL Network

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Andrew J Holland

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Marcin Leda

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The Polo kinase Plk4 functions in centriole duplication

The human microcephaly protein STIL interacts with CPAP and is required for procentriole formation

STIL is required for centriole duplication in human cells

Cep152 acts as a scaffold for recruitment of Plk4 and CPAP to the centrosome

Plk4-induced centriole biogenesis in human cells

p53 protects against genome instability following centriole duplication failure

The PLK4-STIL-SAS-6 module at the core of centriole duplication

De novo formation of centrosomes in vertebrate cells arrested during S phase

Polo-like kinase 4 kinase activity limits centrosome overduplication by autoregulating its own stability.

The Centrioles, Centrosomes, Basal Bodies, and Cilia of Drosophila melanogaster.

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222-235

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scholarly article

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10.1016/J.ISCI.2018.10.003

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English

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Andrew B Goryachev

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2018-10-26T00:00:00Z

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30340068

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6197440

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