Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies - Wikidata - awgldk - TriplyDB

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

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Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies

http://www.wikidata.org/entity/Q58617548

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article publié dans Nature Communications

@fr

im November 2018 veröffentlichter wissenschaftlicher Artikel

@de

scientific article published in Nature Communications

@en

wetenschappelijk artikel

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наукова стаття, опублікована в листопаді 2018

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name

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

@en

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

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type

label

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

@en

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

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prefLabel

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

@en

Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

@nl

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S41467-018-06949-W

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Nature Communications

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Neomorphic PDGFRA extracellula ...... t to PDGFRA targeted therapies

@en

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Christopher P Vellano

http://www.w3.org/2001/XMLSchema#string

Kang Jin Jeong

http://www.w3.org/2001/XMLSchema#string

Kenneth L Scott

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P G Leonard

http://www.w3.org/2001/XMLSchema#string

Patrick K S Ng

http://www.w3.org/2001/XMLSchema#string

Richard Woessner

http://www.w3.org/2001/XMLSchema#string

S H Shao

http://www.w3.org/2001/XMLSchema#string

Xu Hua

http://www.w3.org/2001/XMLSchema#string

Zhenlin Ju

http://www.w3.org/2001/XMLSchema#string

P2860

Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics

Evolutionarily conserved elements in vertebrate, insect, worm, and yeast genomes.

CRAF inhibition induces apoptosis in melanoma cells with non-V600E BRAF mutations

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

Structural and biochemical studies of the PDGFRA kinase domain

A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome.

Gain-of-function mutations of platelet-derived growth factor receptor alpha gene in gastrointestinal stromal tumors.

PDGFRA mutations in gastrointestinal stromal tumors: frequency, spectrum and in vitro sensitivity to imatinib.

Identification of a mutation in the extracellular domain of the Epidermal Growth Factor Receptor conferring cetuximab resistance in colorectal cancer.

Crenolanib inhibits the drug-resistant PDGFRA D842V mutation associated with imatinib-resistant gastrointestinal stromal tumors.

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s41467-018-06949-w

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scholarly article

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10.1038/S41467-018-06949-W

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1

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9

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Gordon B. Mills

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2018-11-02T00:00:00Z

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30389923

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general chemistry

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6214970

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