An update on metabolism studies using human hepatocytes in primary culture
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Evaluation of database-derived pathway development for enabling biomarker discovery for hepatotoxicityHuman embryonic and rat adult stem cells with primitive endoderm-like phenotype can be fated to definitive endoderm, and finally hepatocyte-like cells.Alternative (non-animal) methods for cosmetics testing: current status and future prospects-2010.A high-throughput inhibition screening of major human cytochrome P450 enzymes using an in vitro cocktail and liquid chromatography-tandem mass spectrometry.Organotypic liver culture models: meeting current challenges in toxicity testing.Serum UPLC-MS/MS metabolic profiling in an experimental model for acute-liver injury reveals potential biomarkers for hepatotoxicity.Regulation of human hepatic drug transporter expression by pro-inflammatory cytokines.Microfluidic devices for in vitro studies on liver drug metabolism and toxicity.Cytochrome P450 enzyme regulation by glucocorticoids and consequences in terms of drug interaction.Organs-on-a-chip: a new tool for drug discovery.Competency of different cell models to predict human hepatotoxic drugs.Upgrading HepG2 cells with adenoviral vectors that encode drug-metabolizing enzymes: application for drug hepatotoxicity testing.Advances in high-resolution MS and hepatocyte models solve a long-standing metabolism challenge: the loratadine story.Extending metabolome coverage for untargeted metabolite profiling of adherent cultured hepatic cells.Human hepatocytes derived from pluripotent stem cells: a promising cell model for drug hepatotoxicity screening.In vivo-in vitro-in silico pharmacokinetic modelling in drug development: current status and future directions.Metabolism of synthetic cannabinoids PB-22 and its 5-fluoro analog, 5F-PB-22, by human hepatocyte incubation and high-resolution mass spectrometry.Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism.Alternative Cell Sources to Adult Hepatocytes for Hepatic Cell Therapy.Neonatal livers: a source for the isolation of good-performing hepatocytes for cell transplantation.Human Upcyte Hepatocytes: Characterization of the Hepatic Phenotype and Evaluation for Acute and Long-Term Hepatotoxicity Routine Testing.In vitro 3-D culture demonstrates incompetence in improving maintenance ability of primary hepatocytes
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An update on metabolism studies using human hepatocytes in primary culture
description
article
@en
im Juli 2008 veröffentlichter wissenschaftlicher Artikel
@de
wetenschappelijk artikel
@nl
наукова стаття, опублікована в липні 2008
@uk
name
An update on metabolism studies using human hepatocytes in primary culture
@en
An update on metabolism studies using human hepatocytes in primary culture
@nl
type
label
An update on metabolism studies using human hepatocytes in primary culture
@en
An update on metabolism studies using human hepatocytes in primary culture
@nl
prefLabel
An update on metabolism studies using human hepatocytes in primary culture
@en
An update on metabolism studies using human hepatocytes in primary culture
@nl
P2860
P356
P1476
An update on metabolism studies using human hepatocytes in primary culture
@en
P2093
María José Gómez-Lechón
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P304
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10.1517/17425255.4.7.837
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P577
2008-07-01T00:00:00Z