Synthesis, Bacteriostatic and Anticancer Activity of Novel Phenanthridines Structurally Similar to Benzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and Anticancer Activity of Novel Phenanthridines Structurally Similar to Benzo[c]phenanthridine Alkaloids

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im August 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 27 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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P1476

Synthesis, Bacteriostatic and ...... nzo[c]phenanthridine Alkaloids

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P2093

Kamil Motyka

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Pavel Lasák

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P2860

p53 in the DNA-Damage-Repair Process

Inhibition of topoisomerase I function by nitidine and fagaronine.

Benzo[c]phenanthridine bases and their antituberculosis activity.

Design and preparation of aza-analogues of benzo[c]phenanthridine framework with cytotoxic and antiplasmodial activities.

One-Step Synthetic Access to Isosteric and Potent Anticancer Nitrogen Heterocycles with the Benzo[c]phenanthridine Scaffold.

Anti-tumour activities of a new benzo[c]phenanthridine agent, 2,3-(methylenedioxy)-5-methyl-7-hydroxy-8-methoxybenzo[c]phena nthridini um hydrogensulphate dihydrate (NK109), against several drug-resistant human tumour cell lines.

The Interference of Selected Cytotoxic Alkaloids with the Cytoskeleton: An Insight into Their Modes of Action.

NK314 potentiates antitumor activity with adult T-cell leukemia-lymphoma cells by inhibition of dual targets on topoisomerase II{alpha} and DNA-dependent protein kinase.

Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion.

NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.

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2155

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scholarly article

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10.3390/MOLECULES23092155

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English

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P478

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Vladimír Kryštof

Jakub Stýskala

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2018-08-27T00:00:00Z

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30150591

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6225299

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